Results 31 to 40 of about 10,690 (123)

Epidemiology of fungal diseases in Africa: A review of diagnostic drivers [PDF]

open access: yesCurrent Medical Mycology, 2021
Background and Purpose: There has been a significant increase in the burden of fungal diseases in the last few decades which has imposed a global threat to the health of humans, animals, and plants.
Felix Bongomin, Samuel Fayemiwo
doaj   +1 more source

A multicentre external quality assessment: A first step to standardise PCR protocols for the diagnosis of histoplasmosis and coccidioidomycosis

open access: yesMycoses, Volume 66, Issue 9, Page 774-786, September 2023., 2023
Abstract Background In‐house real‐time PCR (qPCR) is increasingly used to diagnose the so‐called endemic mycoses as commercial assays are not widely available. Objectives To compare the performance of different molecular diagnostic assays for detecting Histoplasma capsulatum and Coccidioides spp. in five European reference laboratories.
Dunja Wilmes   +5 more
wiley   +1 more source

Emerging and re‐emerging fungal threats in Africa

open access: yesParasite Immunology, Volume 45, Issue 2, February 2023., 2023
Abstract The emergence of deadly fungal infections in Africa is primarily driven by a disproportionately high burden of human immunodeficiency virus (HIV) infections, lack of access to quality health care, and the unavailability of effective antifungal drugs.
Rachael Dangarembizi   +2 more
wiley   +1 more source

Fungal exposome, human health, and unmet needs: A 2022 update with special focus on allergy

open access: yesAllergy, Volume 77, Issue 11, Page 3199-3216, November 2022., 2022
Abstract Humans inhale, ingest, and touch thousands of fungi each day. The ubiquity and diversity of the fungal kingdom, reflected by its complex taxonomy, are in sharp contrast with our scarce knowledge about its distribution, pathogenic effects, and effective interventions at the environmental and individual levels.
Joana Vitte   +18 more
wiley   +1 more source

Assessing global fungal threats to humans

open access: yesmLife, Volume 1, Issue 3, Page 223-240, September 2022., 2022
Abstract Fungi are an integral part of the earth's biosphere. They are broadly distributed in all continents and ecosystems and play a diversity of roles. Here, I review our current understanding of fungal threats to humans and describe the major factors that contribute to various threats.
Jianping Xu
wiley   +1 more source

Antimicrobial Importance of Medicinal Plants in Nigeria

open access: yesThe Scientific World Journal, Volume 2020, Issue 1, 2020., 2020
Despite the success of antibiotic discovery, infectious diseases remain the second leading source of death worldwide, while the resistance to antibiotics is among the significant problems in the twenty‐first century. Medicinal plants are very rich in phytochemicals which can be structurally optimized and processed into new drugs.
Harriet U. Ugboko   +5 more
wiley   +1 more source

Cbp1 is conserved among closely related thermally dimorphic fungi that are intracellular pathogens of humans.

open access: yes, 2022
A. Protein alignments of Hc G217B Cbp1 and closely related homologs. The sequences of the Histoplasma homologs (G217B, G186AR, G184A, H88, and H143) highlighted in green, Paracoccidioides homologs (Pb03, Pb18, Pb01, PbCNH, and Pb300) highlighted in blue,
Lucian Duvenage (12908693)   +8 more
core   +1 more source

Chemical constituents and antioxidant capacities of Asparagus africanus Lam.

open access: yesPhytochemistry Letters, 2023
Phytochemical study of the roots and aerial parts of Asparagus africanus Lam. have led to the identification of thirty-three specialized metabolites ( 1-33 ) including two undescribed steroidal saponins: (25 S )-5 β -spirostan-3 β -ol-3- O - β - D ...
Z. Akissi   +4 more
semanticscholar   +1 more source

The role of polyamines in the pathobiology of the emergent fungal pathogen emergomyces africanus [PDF]

open access: yes, 2023
Thesis (MSc)--Stellenbosch University, 2023.ENGLISH ABSTRACT: Emergomyces africanus is an emergent dimorphic pathogen that causes emergomycosis, a systemic fungal infection with severe morbidity and mortality, in immunocompromised patients.
Koroleva, Elizaveta
core  

Structure Elucidation of 16 Undescribed Steroidal Glycosides from the Underground Parts of Agapanthus africanus and Apoptosis-Inducing Activity in Small-Cell Lung Cancer Cell

open access: yesACS Omega, 2023
To explore new candidates for anticancer agents from natural products, the underground parts of Agapanthus africanus, commonly used as an ornamental plant, were investigated phytochemically.
N. Takahashi   +6 more
semanticscholar   +1 more source

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