Results 101 to 110 of about 8,752 (229)
The SUV39 Family of H3K9 Methyltransferases in Skeletal Muscle Stem Cells
FASEB BioAdvances, Volume 7, Issue 6, June 2025.The SUV39 family members are well known for methylating the Lysine 9 of the histone H3 (H3K9) in order to compact the chromatin and contributing to gene repression. We describe their active role in proliferating and differentiating muscle stem cells, how they prevent from inflammation and fibrosis during muscle regeneration and the future avenues ...
Pauline Garcia +2 more
wiley +1 more source
Pharmacogenomics and Personalized Medicine, 2019 Demiao Kong,1,2,* Yi Zhan,3,* Canzhao Liu,4 Yerong Hu,1 Yangzhao Zhou,1,4 Jiawen Luo,1 Lu Gu,1 Xinmin Zhou,1 Zhiwei Zhang1,4 1Department of Cardiovascular Surgery, The Second Xiangya Hospital, Central South University, Changsha, Hunan 410011, China ...
Kong D +8 more
doaj
Emerin increase in regenerating muscle fibers
European Journal of Histochemistry, 2009 The fate of emerin during skeletal muscle regeneration was investigated in an animal model by means of crush injury. Immunofluorescence, immunoblotting and mRNA analysis demonstrated that emerin level is increased in regenerating rat muscle fibers with ...
S Squarzoni +5 more
doaj +1 more source
Glasgow Contributions to the Human Gene Mapping Project, 1959-1987 [PDF]
, 2015 No abstract ...
Ferguson-Smith, Malcolm
core
Lamin A/C Haploinsufficiency Modulates the Differentiation Potential of Mouse Embryonic Stem Cells [PDF]
, 2013 BACKGROUND: Lamins are structural proteins that are the major determinants of nuclear architecture and play important roles in various nuclear functions including gene regulation and cell differentiation.
Chaturvedi, P. +4 more
core +2 more sources
From Doubt to Diagnosis: Canadian Patient Perspectives on a Limb‐Girdle Muscular Dystrophy Diagnosis
Health Expectations, Volume 28, Issue 3, June 2025.ABSTRACT Introduction Limb‐girdle muscular dystrophies (LGMDs) encompass a rare and genetically diverse set of disorders, posing challenges in diagnosis due to the absence of distinct pathological features, leading to frequent misdiagnoses and inadequate symptom management.
Homira Osman +6 more
wiley +1 more source
Best Practice Guidelines on molecular diagnostics in Duchenne/Becker muscular dystrophies [PDF]
, 2010 Meeting participants: Rosário dos Santos, Porto, PortugalIntroduction: A meeting of 29 senior scientists from Europe, the USA, India and Australia, was held in Naarden, The Netherlands on November 14–16, 2008, to establish consensus Best Practice ...
Abbs, S. +5 more
core +2 more sources
The role of inner nuclear membrane protein emerin in myogenesis
The FASEB Journal, Volume 39, Issue 7, 15 April 2025.Emerin function is critical for proper genome reorganization and temporal gene expression necessary for terminal myogenic differentiation. Emerin interacts with both HDAC3 and histone methyltransferases (HMTs) to organize chromatin at the inner nuclear membrane.
Nicholas Marano, James M. Holaska
wiley +1 more source
Myopathic lamin mutations impair nuclear stability in cells and tissue and disrupt nucleo-cytoskeletal coupling [PDF]
, 2017 Lamins are intermediate filament proteins that assemble into a meshwork underneath the inner nuclear membrane, the nuclear lamina. Mutations in the LMNA gene, encoding lamins A and C, cause a variety of diseases collectively called laminopathies.
Dialynas, George +8 more
core
Organelle‐Targeting Nanoparticles
Advanced Science, Volume 12, Issue 7, February 17, 2025.This review examines nanoparticle‐based therapies targeting organelles like the nucleus, mitochondria, and lysosomes. Nanoparticle design, targeting strategies, and their applications in treating diseases linked to organelle dysfunction are discussed, highlighting the potential for improved treatment outcomes and reduced off‐target effects.
John Soukar +2 more
wiley +1 more source