Results 41 to 50 of about 858,047 (299)

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Assessment of genome complementarity in three beef-on-dairy crossbreds reveals sire-specific effects on production traits with comparable rates of genomic inbreeding reduction

BMC Genomics
Background Crossbreeding beef bulls with dairy cows can improve the economic value and fitness of calves not entering dairy production owing to increased meat yield and heterosis.
Dorothea Lindtke, Sylvain Lerch, Isabelle Morel, Markus Neuditschko   +3 more
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Satellite-Derived Estimate of City-Level Methane Emissions from Calgary, Alberta, Canada

Remote Sensing
Cities are important sources of anthropogenic methane emissions. Municipal governments can play a role in reducing those emissions to support climate change mitigation, but they need information on the emission rate to contextualize mitigation actions ...
Zhenyu Xing, Thomas E. Barchyn, Coleman Vollrath, Mozhou Gao, Chris Hugenholtz   +4 more
doaj   +1 more source

A methane emissions reduction equivalence framework for alternative leak detection and repair programs

Elementa: Science of the Anthropocene, 2019
Fugitive methane emissions from the oil and gas sector are typically addressed through periodic leak detection and repair surveys. These surveys, conducted manually using handheld leak detection technologies, are time-consuming.
Thomas A. Fox, Arvind P. Ravikumar, Chris H. Hugenholtz, Daniel Zimmerle, Thomas E. Barchyn, Matthew R. Johnson, David Lyon, Tim Taylor   +7 more
doaj   +1 more source

Renewable Energy Consumption and Carbon Emissions—Testing Nonlinearity for Highly Carbon Emitting Countries [PDF]

, 2021
Sultan Salem, Noman Arshed, Ahsan Anwar, Mubasher Iqbal, Nyla Sattar   +4 more
openalex   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Controllable Introduction of Surface Defects on CH₃NH₃PbI₃ Perovskite

Nanomaterials, 2022
One of the unique characteristics of semiconductors is the strong dependence of their properties on crystal defects and doping. However, due to the species diversity and low density, it is very difficult to control the type and concentration of the ...
Sushu Wan, Yajie Zhu, Daocheng Hong, Yuxi Tian   +3 more
doaj   +1 more source

Estimates of daily oxygen consumption, carbon dioxide and methane emissions, and heat production for beef and dairy cattle using spot gas sampling [PDF]

, 2022
C. Lee, K. A. Beauchemin, J. Dijkstra, D.L. Morris, K. Nichols, P.J. Kononoff, D. Vyas   +6 more
openalex   +1 more source