Results 81 to 90 of about 200,965 (231)

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

open access: yesFEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu   +5 more
wiley   +1 more source

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

open access: yesFEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen   +6 more
wiley   +1 more source

The Effects of Water Temperature on Discharge and Uniformity Parameters of Emitters with Different Discharges, Types and Distances

open access: yesJournal of Agricultural Sciences, 2017
The research was conducted on emitter testing bench established in Irrigation laboratory, Suleyman Demirel University, Isparta, Turkey. In the study, discharge equations q= kHx , standard temperature discharge index TDI, standard temperature is 20 oC ...
Muhammet Sabit Ilkhan, Ulas Senyıgıt
doaj  

Nanophotonic boost of intermolecular energy transfer

open access: yesNew Journal of Physics, 2015
We propose a scheme for efficient long-range energy transfer between two distant light emitters separated by more than one wavelength of light, i.e. much beyond the classical Förster radius. A hybrid nanoantenna-waveguide system mediates the transmission
P M de Roque, N F van Hulst, R Sapienza
doaj   +1 more source

Water application uniformity and fertigation in a dripping irrigation set Uniformidade de aplicação de água e fertirrigação em um conjunto de irrigação por gotejamento

open access: yesEngenharia Agrícola, 2012
The purpose of this study was to evaluate the uniformity of distribution coefficient (UDC) and coefficient of variation (CV) of a familiar set of irrigation, classifying it the ASAE standard.
Adilson L. Borssoi   +4 more
doaj   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

open access: yesFEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi   +7 more
wiley   +1 more source

The Development and Analysis of a Multistage Spraying Method for Liquids in an Ultrasonic Field

open access: yesApplied Sciences
Spraying various liquids (primarily aqueous solutions of various substances) is widely used in various technological processes. For most of them, high dispersibility and a narrow droplet size distribution are essential.
Andrey Shalunov   +4 more
doaj   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

open access: yesFEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida   +6 more
wiley   +1 more source

IRRIGATION FACILITIES FOR DRIP IRRIGATION OF FRUIT-BEARING APPLE TREES CULTIVATED ON CHERNOZEMES IN ROSTOV REGION

open access: yesНаучный журнал Российского НИИ проблем мелиорации, 2019
The purpose of the research is to assess the known and to develop new approaches to determine the number and location of emitters and create irrigation facilities for drip irrigation of fruit-bearing apple trees, taking into account the parameters of ...
A. S. Shtanko, V. N. Shkura
doaj   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

open access: yesFEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth   +6 more
wiley   +1 more source

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