Results 81 to 90 of about 819,721 (331)

Development of a Ground-Based Aerial-Tracking Instrument for Open-Path Spectroscopy to Monitor Atmospheric Constituents [PDF]

open access: yes, 2019
A ground-based aerial-tracking instrument, known as the Ground Tracker, designed to provide spectral data to quantify greenhouse gases is under development.
Hodges, Haden
core   +2 more sources

Spontaneous radiation of a finite-size dipole emitter in hyperbolic media [PDF]

open access: yes, 2011
We study the radiative decay rate and Purcell effect for a finite-size dipole emitter placed in a homogeneous uniaxial medium. We demonstrate that the radiative rate is strongly enhanced when the signs of the longitudinal and transverse dielectric ...
A. Kavokin   +10 more
core   +2 more sources

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Increasing the photon collection rate from a single NV center with a silver mirror

open access: yes, 2014
In the pursuit of realizing quantum optical networks, a large variety of different approaches have been studied to achieve a single photon source on-demand. The common goal for these approaches is to harvest all the emission from a quantum emitter into a
Andersen, Ulrik Lund   +5 more
core   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

open access: yesMolecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad   +12 more
wiley   +1 more source

Control of the electromagnetic environment of a quantum emitter by shaping the vacuum field in a coupled-cavity system

open access: yes, 2015
We propose a scheme for the ultrafast control of the emitter-field coupling rate in cavity quantum electrodynamics. This is achieved by the control of the vacuum field seen by the emitter through a modulation of the optical modes in a coupled-cavity ...
Fiore, Andrea   +4 more
core   +1 more source

Specific Emitter Identification Based on Deep Residual Networks

open access: yesIEEE Access, 2019
Specific emitter identification (SEI) enables the discrimination of individual radio emitters with the external features carried by the received waveforms. This identification technique has been widely adopted in military and civil applications. However,
Yiwei Pan   +4 more
semanticscholar   +1 more source

Highly Efficient Spintronic Terahertz Emitter Enabled by Metal–Dielectric Photonic Crystal [PDF]

open access: yesAdvanced Optical Materials, 2018
Spintronic terahertz (THz) emitter provides the advantages such as apparently broader spectrum, significantly lower cost, and more flexibility compared with the commercial THz emitters, and thus attracts great interest recently.
Zheng Feng   +11 more
semanticscholar   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

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