Results 91 to 100 of about 172,662 (282)

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

open access: yesFEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida   +6 more
wiley   +1 more source

Loss-tolerant architecture for quantum computing with quantum emitters [PDF]

open access: yesQuantum
We develop an architecture for measurement-based quantum computing using photonic quantum emitters. The architecture exploits spin-photon entanglement as resource states and standard Bell measurements of photons for fusing them into a large spin-qubit ...
Matthias C. Löbl   +2 more
doaj   +1 more source

Deterministic coupling of a single silicon-vacancy color center to a photonic crystal cavity in diamond

open access: yes, 2014
Deterministic coupling of single solid-state emitters to nanocavities is the key for integrated quantum information devices. We here fabricate a photonic crystal cavity around a preselected single silicon-vacancy color center in diamond and demonstrate ...
Arend, Carsten   +7 more
core   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

open access: yesFEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth   +6 more
wiley   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel   +4 more
wiley   +1 more source

Tricomponent Exciplex Emitter Realizing over 20% External Quantum Efficiency in Organic Light‐Emitting Diode with Multiple Reverse Intersystem Crossing Channels

open access: yesAdvanced Science, 2019
With the naturally separated frontier molecular orbitals, exciplexes are capable of thermally activated delayed fluorescence emitters for organic light‐emitting diodes (OLEDs).
Ming Zhang   +8 more
doaj   +1 more source

Very bright, near-infrared single photon emitters in diamond

open access: yesAPL Materials, 2013
We demonstrate activation of bright diamond single photon emitters in the near infrared range by thermal annealing alone, i.e., without ion implantation. The activation is crucially dependent on the annealing ambient.
D. W. M. Lau   +6 more
doaj   +1 more source

Cooperative behavior of quantum dipole emitters coupled to a zero-index nanoscale waveguide [PDF]

open access: yes, 2015
We study cooperative behavior of quantum dipole emitters coupled to a rectangular waveguide with dielectric core and silver cladding. We investigate cooperative emission and inter-emitter entanglement generation phenomena for emitters whose resonant ...
Atwater, Harry A., Sokhoyan, Ruzan
core   +1 more source

Deterministic integration of quantum dots into on-chip multi-mode interference beamsplitters using in-situ electron beam lithography

open access: yes, 2017
The development of multi-node quantum optical circuits has attracted great attention in recent years. In particular, interfacing quantum-light sources, gates and detectors on a single chip is highly desirable for the realization of large networks.
Bounouar, Samir   +10 more
core   +2 more sources

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

open access: yesFEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao   +3 more
wiley   +1 more source

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