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Venipuncture and intravenous cannulation are the most common painful procedures performed on children. The most widely used topical anesthetic is eutectic mixture of local anesthetics (EMLA).
Luca Ronfani, Egidio Barbi
exaly +2 more sources
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Purpura Caused by Emla® Is of Toxic Origin
Contact Dermatitis, 1997Emla® cream has been widely used as a local anaesthetic for superficial procedures. Blanching and redness are commonly observed side‐effects. We observed purpura in 5 patients after application of Emla®. Other authors have not reported this before.
Arnold P Oranje
exaly +3 more sources
Dermatologic Surgery, 2004
Topical local anesthetic applications offer painless, effective analgesia with slow onset but prolonged duration and minimal side effects. EMLA (Eczacibasi Pharmaceuticals, Istanbul, Turkey) is the most universally used topical local anesthetic.The aim of this prospective, randomized, double-blind study is to evaluate the efficacy of EMLA on total ...
Nedim, Sarifakioglu +3 more
openaire +2 more sources
Topical local anesthetic applications offer painless, effective analgesia with slow onset but prolonged duration and minimal side effects. EMLA (Eczacibasi Pharmaceuticals, Istanbul, Turkey) is the most universally used topical local anesthetic.The aim of this prospective, randomized, double-blind study is to evaluate the efficacy of EMLA on total ...
Nedim, Sarifakioglu +3 more
openaire +2 more sources
Determinants of success and failure of EMLA
Pain, 1996Although EMLA is known to be an effective topical anesthetic, its rate of success is unknown. Indeed, researchers have suggested that EMLA may fail with young and apprehensive children. Therefore, the objectives of this study were to assess EMLA's rate of success as well as factors which predict success.
J, Lander +5 more
openaire +2 more sources
The Journal of Dermatologic Surgery and Oncology, 1992
A eutectic mixture of local anesthetics (EMLA) contains 2.5% lidocaine and 2.5% prilocaine in an oil and water emulsion and has been found to give effective, safe analgesia on normal and diseased skin, making it useful for numerous medical and surgical procedures, such as anesthesia for superficial surgery, split‐thickness skin grafts, venipuncture ...
openaire +2 more sources
A eutectic mixture of local anesthetics (EMLA) contains 2.5% lidocaine and 2.5% prilocaine in an oil and water emulsion and has been found to give effective, safe analgesia on normal and diseased skin, making it useful for numerous medical and surgical procedures, such as anesthesia for superficial surgery, split‐thickness skin grafts, venipuncture ...
openaire +2 more sources
Damage to Tissue Defenses by EMLA® Cream
Journal of Emergency Medicine, 1991EMLA is a new topical agent that safely anesthetizes intact skin. The purpose of this study was to determine if this cream could be safely used for anesthetizing wounds. This investigation evaluated the potential toxicity of EMLA cream in wounds by measuring its effect on host defenses and on the biology of wound repair.
George T Rodeheaver +2 more
exaly +3 more sources
EMLA for painful procedures in infants
Journal of Pediatric Health Care, 2005Based on the content of the article, you will be able to: Identify the two drugs in EMLA and the youngest pediatric age for its approved use. List the procedures for which EMLA has been used to control pain in infants. Describe the efficacy of EMLA vs. other agents in treating pain. Discuss the potential adverse effects of EMLA in infants.
Karen L, Weise, Milap C, Nahata
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EMLA cream anaesthesia for frenuloplasty
British Journal of Urology, 1995Objective To evaluate the use of a eutectic mixture of local anaesthetics (EMLA) cream as the sole anaesthetic for frenuloplasty. Patients and methods Fifteen patients (mean age 25.6 years, range 19–41) were given topical EMLA cream 30 min before frenuloplasty: a Tegaderm® dressing was applied to keep the anaesthetic in place.
R J, Brough, C D, Betts, S R, Payne
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Penile Absorption of EMLA Cream in Piglets: Implications for Use of EMLA in Neonatal Circumcision
Biology of the Neonate, 2009EMLA® (eutectic mixture of lidocaine and prilocaine) cream is currently not recommended for use in infants < 1 month of age because of the potential risk of methemoglobinemia as a result of the o-toluidine metabolite of prilocaine. We studied bioavailability and changes in methemoglobin levels following topical penile exposure to 1 g of EMLA cream ...
M, Gazarian +4 more
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