Results 151 to 160 of about 1,516,549 (334)

Psychological resilience predicts decreases in pain catastrophizing through positive emotions.

, 2010
Anthony D. Ong, Alex Zautra, M. Carrington Reid   +2 more
openalex   +2 more sources

Diagnosis, Prognosis, and Drug Target Discovery for Chronic Widespread Pain: A Large Proteogenomic Study

Advanced Science, EarlyView.
Plasma proteomics is leveraged to decode the biological underpinnings of chronic widespread pain. A nested machine learning framework integrates proteomic signatures, prospective outcomes, and Mendelian randomization to uncover 18 causal proteins.
Li Chen, Eoin Kelleher, Ruogu Meng, Duanke Liu, Yuchen Guo, Yunhe Wang, Yaqing Gao, Zhe Huang, Zhu Liang, Shuai Yuan, Chao Zeng, Jun Ma, Yanhui Dong, Anushka Irani, Guanghua Lei, Junqing Xie, Daniel Prieto‐Alhambra   +16 more
wiley   +1 more source

LncRNA THUMPD3‐AS1 Regulates Behavioral and Synaptic Structural Abnormalities in Schizophrenia via miR‐485‐5p and ARHGAP8

Advanced Science, EarlyView.
Schizophrenia (SCZ) is linked to synaptic structural deficits driven by dysregulated noncoding RNAs. Using the novel ceRNAxis pipeline, THUMPD3‐AS1/miR‐485‐5p/ARHGAP8 is identified as a key regulator of actin cytoskeletal remodeling through noncanonical RhoB/C‐ROCK2 signaling. Modulating this axis ameliorates SCZ‐like phenotypes in mice and aligns with
Xiaojuan Gong, Lingxi Chen, Xin Guo, Anna Jiang, Yayi He, Chunxia Yan, Liang Ma, Jiayang Gao, Jinyu Zhang, Bao Zhang   +9 more
wiley   +1 more source

Evaluation of Rural Healing Landscape DESIGN Based on Virtual Reality and Electroencephalography

Buildings
From the user’s perspective, emotional elements are increasingly being used in design. Researchers have indicated that healing landscapes in rural areas play a positive role in soothing human emotions.
Hongguo Ren, Xue Wang, Jing Zhang, Lei Zhang, Qingqin Wang   +4 more
doaj   +1 more source

Discovery of a Novel and Potent Kir4.1 Inhibitor as a Safe and Rapid‐Onset Antidepressant Agent in Mice

Advanced Science, EarlyView.
The preferred derivative JX3212 demonstrates strong inhibitory activity against Kir4.1 with favorable druggability and shows significant antidepressant efficacy in vivo. Abstract Major depressive disorder is a serious psychiatric disorder for which novel and fast‐acting antidepressants are required.
Sisi Wang, Xiaoyu Zhou, Mengdan Li, Chao Zhang, Haiyan Xu, Jingyi He, Li Zhan, Yueling Gu, Hao Gu, Tianyu Tu, Hanfang Liu, Taotao Lu, Yueming Zheng, Jian Li, Zhaobing Gao, Yixiang Xu   +15 more
wiley   +1 more source

Author Correction: Comparative analysis of default mode networks in major psychiatric disorders using resting-state EEG

Scientific Reports, 2021
Kang‑Min Choi, Jeong‑Youn Kim, Yong‑Wook Kim, Jung‑Won Han, Chang‑Hwan Im, Seung‑Hwan Lee   +5 more
doaj   +1 more source

Subjective and objective sleep quality modulate emotion regulatory brain function in anxiety and depression

, 2017
Heide Klumpp, J. Scott Roberts, Mary C. Kapella, Amy E. Kennedy, Anand Kumar, K. Luan Phan   +5 more
openalex   +2 more sources

Stress‐Induced Activation of Prolactin‐NR4A1‐Midkine Axis Exacerbates Skin Inflammation

Advanced Science, EarlyView.
Chronic psychological stress activates prolactin signaling to reprogram dermal fibroblasts into APCDD1+ inflammatory effectors via NR4A1, driving midkine secretion. This paracrine hub amplifies keratinocyte proliferation and immune recruitment, thus exacerbating skin inflammation.
Zhiguo Li, Huiyi Quan, Wanting Liu, Jiaoling Chen, Mengyang Chu, Xin Tang, Ke Xue, Xuan Liu, Jingyi Ma, Yaxing Bai, Ruina Dong, Bing Li, Junfeng Hao, Wei Guo, Qingyang Li, Erle Dang, Johann E Gudjonsson, Gang Wang, Shuai Shao   +18 more
wiley   +1 more source

Holocaust or Benevolent Paternalism? Intergenerational Comparisons on Collective Memories and Emotions about Belgium's Colonial Past

, 2010
Laurent Licata, Olivier Klein
openalex   +2 more sources

Recognition of emotion and pain by owners benefits the welfare of donkeys in a challenging working environment

, 2023
Syed S. U. H. Bukhari, Alan G. McElligott, Sarah M. Rosanowski, Rebecca S. V. Parkes   +3 more
openalex   +1 more source