Results 51 to 60 of about 428,503 (362)

A Novel CHMP2B Splicing Variant in Atypical Presentation of Familial Frontotemporal Lobar Degeneration

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT C‐truncating variants in the charged multivesicular body protein 2B (CHMP2B) gene are a rare cause of frontotemporal lobar degeneration (FTLD), previously identified only in Denmark, Belgium, and China. We report a novel CHMP2B splice‐site variant (c.35‐1G>A) associated with familial FTLD in Spain. The cases were two monozygotic male twins who
Sara Rubio‐Guerra, Sara Bernal, David Almenta, Josefina Pérez‐Blanco, Valle Camacho, Isabel Sala, Mª Belén Sánchez‐Saudinós, Jesús García Castro, Judit Selma‐González, Miguel Ángel Santos‐Santos, Álvaro Carbayo, Janina Turon‐Sans, Ricard Rojas‐Garcia, Daniel Alcolea, Juan Fortea, Alberto Lleó, Oriol Dols‐Icardo, Ignacio Illán‐Gala   +17 more
wiley   +1 more source

Impaired regulation of emotion: Neural correlates of reappraisal and distraction in bipolar disorder and unaffected relatives [PDF]

, 2015
Deficient emotion regulation has been proposed as a crucial pathological mechanism in bipolar disorder (BD). We therefore investigated emotion regulation impairments in BD, the related neural underpinnings and their etiological relevance for the disorder.
Forneck, J., Kanske, P., Schönfelder, S., Wessa, M.   +3 more
core   +3 more sources

Comorbidity between depression and anxiety: assessing the role of bridge mental states in dynamic psychological networks

BMC Medicine, 2020
Background Comorbidity between depressive and anxiety disorders is common. A hypothesis of the network perspective on psychopathology is that comorbidity arises due to the interplay of symptoms shared by both disorders, with overlapping symptoms acting ...
Robin N. Groen, Oisín Ryan, Johanna T. W. Wigman, Harriëtte Riese, Brenda W. J. H. Penninx, Erik J. Giltay, Marieke Wichers, Catharina A. Hartman   +7 more
doaj   +1 more source

Anticipating manic and depressive transitions in patients with bipolar disorder using early warning signals

International Journal of Bipolar Disorders, 2022
Background In bipolar disorder treatment, accurate episode prediction is paramount but remains difficult. A novel idiographic approach to prediction is to monitor generic early warning signals (EWS), which may manifest in symptom dynamics. EWS could thus
Fionneke M. Bos, Marieke J. Schreuder, Sandip V. George, Bennard Doornbos, Richard Bruggeman, Lian van der Krieke, Bartholomeus C. M. Haarman, Marieke Wichers, Evelien Snippe   +8 more
doaj   +1 more source

Technological Interventions for Emotion Regulation

, 2022
This dissertation describes a way of organising the ample existing evidence in the field of digital mental health. For that purpose the DIU framework is presented (D for dissemination, I for improvement and U for understanding). This framework is applied to the specific field of emotion regulation in emotional disorders.
Javier Fernandez-Álvarez, Amanda Díaz-García, Desirée Colombo, Cristina Botella, Pietro Cipresso, Giuseppe Riva   +5 more
openaire   +4 more sources

Cerebello‐Prefrontal Connectivity Underlying Cognitive Dysfunction in Spinocerebellar Ataxia Type 2

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinocerebellar ataxia type 2 (SCA2) is a hereditary cerebellar degenerative disorder, with motor and cognitive symptoms. The constellation of cognitive symptoms due to cerebellar degeneration is named cerebellar cognitive affective syndrome (CCAS), which has increasingly been recognized to profoundly impact patients' quality of life;
Ami Kumar, Ruo‐Yah Lai, Zena Fadel, Yicheng Lin, Pia Parekh, Rachel Griep, Ming‐Kai Pan, Sheng‐Han Kuo   +7 more
wiley   +1 more source

Anger, Affective Injustice, and Emotion Regulation [PDF]

, 2019
Victims of oppression are often called to let go of their anger in order to facilitate better discussion to bring about the end of their oppression. According to Amia Srinivasan, this constitutes an affective injustice.
Archer, Alfred, Mills, Georgina
core   +2 more sources

Integrating personalized experience sampling in psychotherapy: A case illustration of the Therap-i module

Heliyon, 2023
Background: The experience sampling methodology (ESM) is increasingly being suggested as a clinical tool in mental health care, as it offers ecologically valid, microlevel information on psychopathological processes.
Lino von Klipstein, Michelle N. Servaas, Robert A. Schoevers, Date C. van der Veen, Harriëtte Riese   +4 more
doaj  

The Mediating Role of Emotion Regulation Within the Relationship Between Neuroticism and Misophonia: A Preliminary Investigation

Frontiers in Psychiatry, 2020
Misophonia is a newly described condition characterized by heightened emotional reactivity (e.g., anger, anxiety, and disgust) to common repetitive sounds (e.g., oral or nasal sounds made by others), accompanied by difficulties responding to these sounds
Clair Cassiello-Robbins, Deepika Anand, Kibby McMahon, Kibby McMahon, Rachel Guetta, Rachel Guetta, Jacqueline Trumbull, Jacqueline Trumbull, Lisalynn Kelley, M. Zachary Rosenthal, M. Zachary Rosenthal   +10 more
doaj   +1 more source

Cortical Excitability Before and After Long‐Term Perampanel Treatment for Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Antiseizure medications (ASMs), which may influence cortical excitability, are the mainstay of epilepsy treatment. Transcranial magnetic stimulation (TMS) helps evaluate cortical excitability. We assessed changes in TMS responses using serial TMS measurements in people treated with an adjunctive noncompetitive AMPA‐receptor ...
Robert M. Helling, Johannes P. van Dijk, Prisca R. Bauer, Roland D. Thijs, Josemir W. Sander, Machiel Zwarts, Gerhard H. Visser   +6 more
wiley   +1 more source