Results 41 to 50 of about 745,436 (297)
This study reveals that Urolithin A (UA) counteracts alcohol‐induced cognitive and social dysfunction (AICSD) via a gut microbiome‐dependent mechanism. UA‐enriched Bacteroids sartorii and Parabacteroids distasonis elevate anandamide (AEA), which activates the CB1R‐DRD2‐Rap1 signaling cascade to drive synaptic repair and reduce neuroinflammation ...
Hongbo Zhang +9 more
wiley +1 more source
The Mediating Role of Early Maladaptive Schemas in the Relationships of Emotional Maltreatment and Emotional Disorders [PDF]
Although the consequences of emotional maltreatment have not been extensively investigated, experiences of emotional maltreatment or abuse have been associated with powerful and enduring psychological problems.
Abdolahzadeh Rafi, Mahdi +2 more
core +1 more source
Navigating the Ethereal Tightrope: The Nanogenerator Manipulates Neurons for Immune Equilibrium
This review explores how nanogenerators modulate neuroimmune responses, offering innovative strategies for treating neurological disorders. By interfacing with neural pathways, they enable precise control of immune activity, especially via vagus nerve stimulation.
Jia Du +5 more
wiley +1 more source
The Role of Religion as a Mediator between Emotional Abuse and Emotional Disorders in Adolescents [PDF]
The present study intended to determine the extent to which religion is significant as a mediator between emotional abuse and emotional disorders in adolescents, and it followed a correlational research design.
Mehdi Abdollahzadeh Rafi
doaj
BackgroundThe dysregulation of glucose homeostasis via mental health stress is increasingly acknowledged, whereby depression independently increases the risk of the onset of type 2 diabetes by up to 60%.
Seryan Atasoy +13 more
doaj +1 more source
Clarifying the Effects of Parental Substance Abuse, Child Sexual Abuse, and Parental Caregiving on Adult Adjustment [PDF]
Parental alcoholism, childhood sexual abuse, and other forms of child maltreatment are generally viewed as contributing to adult adjustment problems. The long-term effects of these various factors, however, are actually not well understood.
Melchert, Timothy
core +1 more source
This study reveals that chronic alcohol exposure selectively upregulates ACSL1 expression in prefrontal cortical microglia, driving lipid metabolism reprogramming and lipid droplet accumulation, which activates the NLRP3 inflammasome and sustains neuroinflammation. To reverse this process, a dual‐targeted lipid nanoparticle, siACSL1@LNP‐MR, is designed
Liang Hao +8 more
wiley +1 more source
Background Emotional abuse is central to other forms of abuse. The primary objective of this paper was to estimate the prevalence of emotional abuse among pupils in basic education schools and the risk factors associated with it in Aden governorate ...
Ba- Saddik Amal S S, Hattab Abdullah S
doaj +1 more source
Total Estimated Cost of Child Abuse and Neglect in the United States [PDF]
Outlines the direct and indirect costs of addressing the physical, emotional, social, and cognitive impact of abuse and neglect on the victims, including health care, child welfare services, law enforcement, special education, and lost ...
Ching-Tung Wang, John Holton
core
ABSTRACT Immune homeostasis is indispensable for preserving organismal integrity, orchestrated through complex molecular networks encompassing immune cell dynamics, microbial cues, and epigenetic regulation. Among these, the gut microbiota‐non‐coding RNA (ncRNA) axis has recently garnered substantial attention as a multifaceted modulator of host ...
Bonan Chen +12 more
wiley +1 more source

