Advanced Science, EarlyView.Frontal lobe traumatic brain injury is associated with hyperactivity of an insular–orbitofrontal circuit in both patients and mice. By combination of integrating functional imaging, cell‐type–specific circuit manipulation, single‐cell transcriptomics, and whole‐cell recordings, this work identifies the downregulation of the potassium channel KCNC3 in ...
Meng‐Ge Li +10 more
wiley +1 more source
Psycho-emotional adjustment in parents of adolescents: A cross-sectional and longitudinal analysis of the impact of the COVID pandemic. [PDF]
J Pediatr Nurs, 2021 Valero-Moreno S +4 more
europepmc +1 more source
VlPAG/DRN Microglia Drive Neuropathic Pain‐Induced Depression via a Defined Neuroimmune Axis
Advanced Science, EarlyView.Peripheral nerve injury (SNI) induces neuropathic pain, activates midbrain microglia, and triggers an NLRP3–IL‐1β–dependent inflammatory cascade. IL‐1β signals through IL‐1R1 on vlPAG/DRN VGLUT2+ neurons (vlPAG/DRNGlu), inducing hyperexcitability and driving the vlPAG/DRNGlu→BNSTGABA circuit to produce the affective component of neuropathic pain ...
Jing Yang +7 more
wiley +1 more source
Health behavior adherence and emotional adjustment during the COVID-19 pandemic in a US nationally representative sample: The roles of prosocial motivation and gratitude. [PDF]
Soc Sci Med, 2021 Nelson-Coffey SK +4 more
europepmc +1 more source
Advanced Science, EarlyView.Tissue incision induces CXCL5 release, which activates neuronal CXCR2 on incision‐innervating sensory neurons. Neuronal CXCR2 couples with TRPA1 to drive mechanical pain and engages p38 MAPK signaling to upregulate TRPV1 and promote heat pain. Targeted Cxcr2 knockdown relieves incisional pain while preserving CXCR2‐dependent neutrophil responses ...
Yushuang Pan +10 more
wiley +1 more source
Predicting Cyberbullying Based on Emotional Maturity, Parent-Child Relationship, and School Adjustment in Adolescents [PDF]
مجله علوم روانشناختیBackground: Cyber aggression, as an intentional and harmful behavior in cyberspace—such as insults, rumor-spreading, or threats—has become a serious and growing issue among adolescents.
Nafiseh Abedi +2 more
doaj
The effectiveness of proactive coping intervention for students with learning disabilities
Discover PsychologyThe presence of Learning Disabilities (LD) increases the possibility of psychological distress due to the negative school experiences. Apart from academic difficulties, students with LD are facing social and emotional problems related to their ...
D. P. Deepthi +3 more
doaj +1 more source
Advanced Science, EarlyView.Androgenetic alopecia (AGA) is a common form of hair loss with limited treatment options. Silencing of WNT5A signaling, which is widely known as the trigger of the ncWNT signaling pathway, happens in hair follicle stem cells from balding areas. It leads to downregulation of ATF3 and its target FOSB.
Ruiyu Luo +10 more
wiley +1 more source
Social and Emotional Competence: Are preventive programmes necessary in early childhood education and care? [PDF]
, 2010 Just as young children begin to develop a wide range of skills, attitudes and behaviours during the early years, the development of social and emotional competence is also rooted in early childhood. Yet, whilst some argue that this competence is nurtured
Sollars, Valerie, Valerie Sollars
core +1 more source
Emotional, Social and Occupational Adjustment among Oncology Nurses
International Journal of Hematology-Oncology and Stem Cell Research, 2016 Background: Social, occupational and emotional adjustment of Oncology nurses were assessed and compared with other nurses in this study. Subjects and Methods: One hundred nurses including Oncology nurses (n=50) and non-Oncology nurses (n=50) participated
Mohammad Vaezi +4 more
doaj