Results 101 to 110 of about 73,117 (266)

Chronic Prostatitis/Chronic Pelvic Pain Syndrome: Research Progress and Precision Diagnosis‐Therapy Under the Integrated Neuro–Immune–Metabolic–Microbiota Axis Framework

open access: yesiMetaMed, EarlyView.
Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is increasingly recognized as a systemic disorder rather than a purely local prostate disease. The diagram illustrates the transition from the traditional local prostate‐centered model to a multi‐axis systemic framework involving clinical heterogeneity, local prostatic inflammation, systemic ...
Kun Wang   +10 more
wiley   +1 more source

Human biomarker navigator

open access: yesiMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li   +29 more
wiley   +1 more source

Emotional Dysregulation and Sleep Problems: A Transdiagnostic Approach in Youth

open access: yesClinics and Practice
Background: Sleep is a complex phenomenon that affects several aspects of life, including cognitive functioning, emotional regulation, and overall well-being.
Gianluca Sesso   +9 more
doaj   +1 more source

High‐Sugar Diet and Intestinal Diseases: A Shared Microbiota–Barrier–Immunity–Metabolism Axis in Inflammatory Bowel Disease, Food Allergy, and Colorectal Cancer

open access: yesiNew Medicine, EarlyView.
ABSTRACT The global incidence of intestinal diseases—including food allergy, inflammatory bowel disease (IBD), and colorectal cancer (CRC)—continues to escalate in parallel with the expansion of the “Western diet,” within which the high‐sugar diet (HSD) has emerged as a pivotal yet under‐recognized dietary driver.
Yuchen Wang   +9 more
wiley   +1 more source

Bidirectional Pathological Axis Between Alzheimer's Disease and Circadian Rhythm Disturbance: Mechanisms and Therapeutic Strategies

open access: yesiNew Medicine, EarlyView.
This graphical abstract illustrates a bidirectional vicious cycle between Alzheimer’s disease (AD) and circadian rhythm disturbance (CRD). On the one hand, AD pathology, including amyloid‐β (Aβ) plaque deposition and tau hyperphosphorylation, may damage the suprachiasmatic nucleus (SCN) and disrupt melatonin signaling, leading to sleep fragmentation ...
Jiajia Qin   +10 more
wiley   +1 more source

Effectiveness of social-emotional learning program on psychological distress and dysregulation in students with specific learning disorders

open access: yesBMC Psychology
This study investigates the effectiveness of a social-emotional skills training program on emotional dysregulation and psychological distress among students with Specific Learning Disorders (SLD).
Shahrooz Nemati   +3 more
doaj   +1 more source

Analysis of individualized brain–gut association networks and transcriptional patterns in major depressive disorder

open access: yesInterdisciplinary Medicine, EarlyView.
Individualized brain–gut association networks suggest potential neuropathological mechanisms in MDD and MDDSI. Multilevel brain–gut association changes involving HSV‐1 and inflammation may be relevant to MDD, whereas alterations related to insulin metabolism may play a potential role in the neuropathological mechanisms of MDDSI.
Wei Wang   +10 more
wiley   +1 more source

Specific peptide enrichment strategies for neuropsychiatric disorders: From material design to diagnostic applications

open access: yesInterdisciplinary Medicine, EarlyView.
This review outlines specific peptide enrichment strategies, including metal, magnetic oxides, functional polymers, and antibody‐based approaches, and their mechanisms, highlighting applications in biomarker discovery for major neurological and psychiatric disorders.
Xue Zhang   +8 more
wiley   +1 more source

Prevalence and correlates of emotional dysregulation in clinical versus community samples of Egyptian youth

open access: yesMiddle East Current Psychiatry
Background Self-regulation is a core phenomenon in child psychology. The Dysregulation Profile (DP), a composite scale that results from adding up three scores of the Child Behavior Checklist (CBCL 6–18), has emerged during the last two decades as a ...
Mohammad A. Seleem, Masha Y. Ivanova
doaj   +1 more source

Exposure to Family Violence and Adolescent Antisocial Behavior: Exploring the Differential Onset and Growth Rates of Mediational Impulsive Tendencies

open access: yesJournal of Adolescence, EarlyView.
ABSTRACT Introduction Adolescent externalizing symptoms, including aggression, impulsivity, and rule‐breaking, are prevalent and often co‐occur. Etiologically, developmental scientists have utilized developmental models to explain the link between exposure to family violence and adolescent externalizing symptoms; however, few studies have tested the ...
Timothy I. Lawrence   +4 more
wiley   +1 more source

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