Results 171 to 180 of about 65,528 (262)

Monogenic and syndromic obesity in children: Clinical recognition, genetics, and precision management

Pediatric Investigation, EarlyView.
Monogenic and syndromic obesity in children often arises from defects in the leptin–melanocortin pathway. Understanding these rare genetic causes not only clarifies mechanisms of appetite regulation but also enables precision therapies, offering hope beyond lifestyle interventions.
Hadel Khalil, Eugene Feigin, Hussein Zaitoon   +2 more
wiley   +1 more source

Emotional dysregulation, obsessive-compulsive traits, and eating disorders: three constructs for one spectrum? [PDF]

J Endocrinol Invest
Tempia Valenta S, Beghelli V, Marcolini F, Rosinska M, De Ronchi D, Fernandez-Aranda F, Atti AR.   +6 more
europepmc   +1 more source

Stem cell–mediated neuroplasticity and psychological recovery in cancer survivors: Mechanisms, evidence, and translational challenges

Precision Medical Sciences, EarlyView.
Cancer therapies can trigger neuroinflammation and disrupted neuroplasticity, contributing to cognitive impairment and psychological distress in survivors. Stem cells (NSCs/MSCs) and their extracellular vesicles may restore neural niches via trophic support, immunomodulation, synaptic remodeling, and vascular repair, but require rigorous safety, dosing,
Xinyi Yang
wiley   +1 more source

Endocrine therapy‐induced cancer‐related fatigue in hormone‐dependent malignancies: Mechanisms, impact, and management strategies

Precision Medical Sciences, EarlyView.
Multipathway schematic of endocrine therapy–induced cancer‐related fatigue. Endocrine interventions trigger four interacting mechanisms—neuroendocrine dysregulation, systemic inflammation, energy‐metabolic failure, and psycho‐behavioral amplification—that culminate in the multidimensional CRF phenotype.
Jiajing Jiang, Jun Lu, Sen Qin, Ruzhou Chen, Qiuchen Zhang, Lvqi He, Yubei Li, Jingyao Yan   +7 more
wiley   +1 more source

Psoriasis and Emotional Dysregulation: A Multicenter Analysis of Psychodermatology Outcomes. [PDF]

Dermatol Pract Concept
Samela T, Moretta G, Provini A, Pagnanelli G, Bonifati C, Graceffa D, Lora V, Orsini D, Zangrilli A, Giordano D, Dattola A, Richetta A, Bernardini N, Caldarola G, De Luca E, Masini C, Bavetta M, Tribuzi P, Panasiti V, Abeni D.   +19 more
europepmc   +1 more source

Optimizing acupuncture dosing for hormone therapy‐induced hot flashes in cancer patients: A regression‐based analysis and narrative review

Precision Medical Sciences, EarlyView.
Our analysis reveals a clear dose–response relationship between acupuncture sessions and the reduction of hormone therapy‐induced hot flashes. A threshold of approximately 10 sessions establishes a robust quantitative benchmark for achieving clinically meaningful neuro‐autonomic modulation and symptom relief.
Jiaming Cui, Xinyao Wei, Lulu Bin, Shaoxin Sun, Yu Liu, Tao Yang, Zhishun Liu, Jiani Wu   +7 more
wiley   +1 more source

A comprehensive Sustainable Development Goal‐guided framework for advancing survivorship, rehabilitation, and quality of life in breast cancer patients

Precision Medical Sciences, EarlyView.
This article presents an Sustainable Development Goal‐aligned framework integrating survivorship care, rehabilitation, and quality‐of‐life strategies for breast cancer patients, emphasizing equity, gender responsiveness, and health system strengthening. It highlights multidisciplinary, patient‐centered interventions and global partnerships as essential
Emmanuel Ifeanyi Obeagu
wiley   +1 more source

Gambling Disorder and Romantic Relationships: The role of positive communication and emotional dysregulation in couple satisfaction. [PDF]

J Gambl Stud
Macía L, Saratxaga I, Álvarez-González A, Iraurgui I, Estévez A.   +4 more
europepmc   +1 more source

The Neuroprotective Effect of a Waste Byproduct Obtained From Pomegranate (Punica granatum)

Phytotherapy Research, EarlyView.
The Effect of a Waste Byproduct Obtained From Pomegranate on Neurodegeneration. ABSTRACT Pomegranate is an exceptional fruit that can have several beneficial effects on human health. The peel of pomegranate, a waste product, should be recovered as it still contains valuable constituents, including phenolic compounds, minerals and fibre. The recovery of
Jessica Maiuolo, Valeria Mazza, Rosamaria Caminiti, Francesca Oppedisano, Saverio Nucera, Salvatore Ragusa, Sara Ilari, Lucia Carmela Passacatini, Luigi Tucci, Giuseppe Trunfio, Vincenzo Mollace, Carolina Muscoli   +11 more
wiley   +1 more source