Results 191 to 200 of about 123,753 (311)

Immune involvement in neuropsychiatric disorders: Insights from single‐cell transcriptomic studies

open access: yesPsychiatry and Clinical Neurosciences, EarlyView.
Neuropsychiatric disorders pose profound challenges to both research and treatment, largely due to their clinical heterogeneity and the limited understanding of their underlying biological mechanisms. While bulk RNA sequencing (bulk RNA‐seq) has been widely used to study gene expression, it cannot resolve cell‐type‐specific signals or detect rare ...
Tsutomu Takeda   +4 more
wiley   +1 more source

Overall quality of life and emotional regulation among inmates: A narrative review

open access: yesPsychiatry and Clinical Neurosciences, EarlyView.
Although there is a plethora of studies related to quality of life (QoL), little is known about QoL in prison settings. Emotions and difficulties in emotional regulation in incarcerated individuals may affect inmates' QoL and also their ability to reintegrate into society.
Kalliopi Megari   +2 more
wiley   +1 more source

The development of positron emission tomography (PET) tracer for glutamate AMPA receptors and its application to human biology and clinics

open access: yesPsychiatry and Clinical Neurosciences, EarlyView.
Psychiatric and neurological disorders severely compromised patients' quality of life. Despite their urgent needs, the development of diagnostics and therapeutics based on the biological basis has made only little progress. This is due to limited evidence on the biological basis of these disorders in humans. Synapses are fundamental structural units of
Mai Hatano, Hiroki Abe, Takuya Takahashi
wiley   +1 more source

Blurred Lines: Leveraging Business Model Ambiguity for Innovation and Agility

open access: yesR&D Management, EarlyView.
ABSTRACT Earlier research has established the cognitive perspective on business models (BM) and business model innovation (BMI), which predominantly assumes that the understanding and interpretation of established BMs are uniform among organizational actors.
Pascal Breitenmoser   +2 more
wiley   +1 more source

Reengaging Criminology in Regulation and Governance: A Synergistic Research Agenda on Regulatory Guardianship

open access: yesRegulation &Governance, EarlyView.
ABSTRACT Recent literature calls for scholars to bridge the divide that has emerged between criminology and regulation and governance. In the current work, we propose that criminological opportunity theories provide one fruitful pathway to that end.
Carole Gibbs   +3 more
wiley   +1 more source

The Role of Psychological Inflexibility in Adolescents' Loneliness: School Friendship Closeness as a Mediator

open access: yesScandinavian Journal of Psychology, EarlyView.
ABSTRACT This study aimed to expand knowledge on the roles of psychological inflexibility and school friendship closeness in adolescents' loneliness during the transition to upper secondary education. The participants were 885 Finnish adolescents (mean age = 15.74, SD = 0.37, 56% girls). Loneliness was measured twice: in Grade 9 and at the beginning of
Annina Jormanainen   +5 more
wiley   +1 more source

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