Results 71 to 80 of about 123,753 (311)
This study reveals that chronic alcohol exposure selectively upregulates ACSL1 expression in prefrontal cortical microglia, driving lipid metabolism reprogramming and lipid droplet accumulation, which activates the NLRP3 inflammasome and sustains neuroinflammation. To reverse this process, a dual‐targeted lipid nanoparticle, siACSL1@LNP‐MR, is designed
Liang Hao +8 more
wiley +1 more source
Men with intellectual disabilities with a history of sexual offending: empathy for victims of sexual and non-sexual crimes [PDF]
Background: The objectives were (a) to compare the general empathy abilities of men with intellectual disabilities (IDs) who had a history of sexual offending to men with IDs who had no known history of illegal behaviour, and (b) to determine whether men
Baron-Cohen +82 more
core +1 more source
Monoaminylation in Human Health and Disease: State of the Field, Challenges, and Emerging Directions
This review delineates monoaminylation—serotonylation, dopaminylation, and histaminylation—as key post‐translational modifications beyond receptor signaling. It details their catalytic mechanisms, roles in gene expression and protein function, and implications in health and disease, aiming to bridge mechanistic insights with therapeutic potential ...
Yiqi Zhao +4 more
wiley +1 more source
Abstract We explored community‐based doulas' perspectives on the acceptability of using formal screening tools to address low rates of mental health screening, diagnosis, and treatment for perinatal anxiety and depression among Black women. Using thematic analysis, we analyzed interview data from 30 community‐based doulas who support Black families ...
Tamara Nelson +5 more
wiley +1 more source
The cumulative effect of EA analgesia is partially attributed to the activation of EA‐TRAPed cells in ACC. Multiple EA sessions and single EA sessions activated different neuronal populations in the ACC. The enhanced analgesic effect of multiple EA sessions may be attributed to an increase in the proportion of GABAergic neurons within the ACC. Abstract
Zi Guo +8 more
wiley +1 more source
Moving beyond neurophobia to cultivate the neuroquisitive learner
Abstract “Neurophobia,” a pervasive fear of the neurological sciences, poses a significant barrier in medical education, affecting learners and physicians worldwide. Its consequences are far‐reaching, contributing to a limited neurology workforce and diminished confidence among non‐specialists in managing neurological conditions.
Joanna R. Appel +1 more
wiley +1 more source
The Minds of Black Women — Impacts on Mental Health and Well-Being Across Collective Identities and Experience [PDF]
Limited research investigates how structural and institutional barriers affect Black women's mental health. Further, stereotypes and tropes such as the Angry Black Woman and Strong Black Woman are impactful. Black women's proximity to wellness is largely
Campbell, Kayla
core
Mapping dynamic interactions among cognitive biases in depression [PDF]
Depression is theorized to be caused in part by biased cognitive processing of emotional information. Yet, prior research has adopted a reductionist approach that does not characterize how biases in cognitive processes such as attention and memory work ...
Bernstein, Amit +3 more
core +1 more source
ABSTRACT Parental stress influences parent–child interactions in typical development and is a prognostic factor of autism outcome. However, we still do not know to what extent parental stress affects parent–child interactions and whether caregiver role matters.
Maria Grazia Logrieco +11 more
wiley +1 more source
Effectiveness of emotional schema therapy on death attitude and distress tolerance of breast cancer patients [PDF]
Aim and Background: Breast cancer is the most common malignancy in women, and despite medical advances and the development of treatments, this disease continues to cause psychological and physical effects on the life dimensions of many affected people ...
Gholamreza Talebi +3 more
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