Results 181 to 190 of about 19,601 (263)

The genetic architecture of epilepsy across molecular mechanisms and clinical heterogeneity

Epilepsia Open, EarlyView.
Abstract Epilepsy comprises a highly heterogeneous group of neurological disorders unified by a persistent predisposition to recurrent seizures, yet driven by remarkably diverse genetic, molecular, and network‐level mechanisms. Advances in genomic technologies have revealed that epilepsy arises from a multilayered genetic architecture encompassing rare
Mohammad Reza Seyedtaghia, Jina Babanzadeh, Marcello Scala, Lorenzo Perilli, Pasquale Striano   +4 more
wiley   +1 more source

Novel insights into SGLT2 inhibitor efficacy in heart failure: A meta-analysis employing win ratio, hazard ratio, and risk ratio. [PDF]

Am Heart J Plus
Nasrollahizadeh A, Javankiani S, Rahmati S, Nasrollahizadeh A, Hakim D, Modin D, Johansen ND, Biering-Sørensen T, Hosseini K.   +8 more
europepmc   +1 more source

Learning Rocking Dynamics From Sparse Shake‐Table Data With Interpretable Physics‐Informed Neural Networks

Earthquake Engineering &Structural Dynamics, EarlyView.
ABSTRACT We present a hybrid interpretable Physics‐Informed Neural Network Long‐Short Term Memory (Hybrid PINN LSTM) framework for predicting the seismic response of rocking blocks. Existing analytical models rely on uncertain idealizations, while purely data‐driven and machine‐learning approaches lack physical consistency and interpretability.
Shirley Shen, Christian Málaga‐Chuquitaype   +1 more
wiley   +1 more source

Practical Guidance on Implementation of Guideline-Directed Medical Therapy in the Management of Heart Failure: Expert Opinion From the Middle East and Africa Region. [PDF]

J Am Heart Assoc
Doku A, El-Harari M, Badr A, Bennis A, Ogola E, Alhabeeb W, Abdelhamid M, Mbakwem AC.   +7 more
europepmc   +1 more source

Rocking and Rolling of Rigid Polygons Under Seismic Excitation

Earthquake Engineering &Structural Dynamics, EarlyView.
ABSTRACT We present an event driven analytical framework for rigid cyclic polygons subjected to horizontal ground excitation in which uplift, impact, and successive pivot switching are treated within a unified non‐smooth dynamical description. Rolling is defined as a sequence of energetically admissible transitions between neighbouring vertices tied to
Atif Rasheed, Christian Málaga‐Chuquitaype   +1 more
wiley   +1 more source

Effect of Empagliflozin on Cardiovascular Mortality and Heart Failure Hospitalizations: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. [PDF]

Cureus
Rauf U, Ansar F, Ali MS, Chudhary F, Zafar MH, Azzam A, Amjad MA, Siddique MQ, Rauf MS, Ahmad MB.   +9 more
europepmc   +1 more source

Climate Driven Water Table Changes and Their Influence on Liquefaction Response of Integral Bridges

Earthquake Engineering &Structural Dynamics, EarlyView.
ABSTRACT Integral abutment bridges (IABs) eliminate bearings and joints but transfer seismic demand directly into the surrounding soil, making their response highly sensitive to groundwater conditions and soil–structure interaction. This study presents a 60 g centrifuge testing programme on single‐span IABs designed to isolate the influence of water ...
Yazan B. Asia, Gopal S. P. Madabhushi
wiley   +1 more source

Obesity and Heart Failure: Introducing the Theme. [PDF]

J Cardiovasc Dev Dis
Monitillo F, Basile P, Lisco G.
europepmc   +1 more source

Calorie‐Free Menus as a Potential Mitigation Strategy for Mandatory Calorie Labelling: Evidence From People With Disordered Eating in England

European Eating Disorders Review, EarlyView.
ABSTRACT Objective Since the introduction of mandatory out‐of‐home calorie labelling in England, concerns have been raised about potential negative impacts on people with disordered eating. To mitigate these concerns, food outlets can provide calorie‐free menus on request.
Nora Trompeter, Abinaya Nadarajah, Fiona Duffy, Helen Sharpe, Ellen Maloney, Ulrike Schmidt, Lucy Serpell, Dasha Nicholls, Tom Jewell   +8 more
wiley   +1 more source

Cost-Effectiveness of Empagliflozin in Patients with Chronic Heart Failure Irrespective of Left-Ventricle Ejection Fraction in the Netherlands. [PDF]

Am J Cardiovasc Drugs
Slob BPH, Postma MJ, Weersma M, Rocca HB, de Jong LA, Boersma C.   +5 more
europepmc   +1 more source