Results 111 to 120 of about 188,190 (286)

Stabilized Extracellular Vesicle Formulations for Inhalable Dry Powder Development

open access: yesSmall, EarlyView.
Extracellular vesicles (EVs) hold promise for chronic obstructive pulmonary disease (COPD) treatment but face challenges with storage and delivery. This study demonstrates the stabilization of lung fibroblast‐derived EVs using inulin, enabling freeze‐drying and spray‐drying.
Eva M. Jansen   +7 more
wiley   +1 more source

Air emphysema after drying the cavity with an air syringe [PDF]

open access: diamond, 2018
Ewa Marek   +3 more
openalex   +1 more source

CT-based emphysema characterization per lobe: A proof of concept [PDF]

open access: hybrid, 2023
Hendrik Joost Wisselink   +11 more
openalex   +1 more source

Clinical characteristics of immediate allergic adverse reactions to intravenous amoxicillin‒clavulanic acid in conscious dogs

open access: yesVeterinary Record, EarlyView.
Abstract Background Amoxicillin‒clavulanic acid (AMC) is one of the most frequently used antibiotics in small animal practice, and reports on adverse reactions are scarce. The aim of this study was to describe the clinical characteristics of immediate allergic adverse reactions to intravenous (IV) AMC in conscious dogs. Methods The medical records of a
Leonel Frutuoso, Anna Threlfall
wiley   +1 more source

Low income as a determinant of exercise capacity in COPD. [PDF]

open access: yes, 2019
Exercise capacity (EC) is a critical outcome in chronic obstructive lung disease (chronic obstructive pulmonary disease (COPD)). It measures the impact of the disease and the effect of specific interventions like pulmonary rehabilitation (PR).
Benzo, Roberto   +4 more
core  

Electronic health records improve the diagnosis and prognosis of pulmonary fungal infections in lung cancer patients

open access: yesVIEW, EarlyView.
Pulmonary fungal infections are life‐threatening complications in lung cancer patients, posing significant challenges in clinical management. To address this, we developed machine learning tools that translate routine electronic health record data into actionable insights for diagnosing infections and assessing prognosis.
Hongwei Meng   +14 more
wiley   +1 more source

Marked Reversibility of Functional Small Airway Disease Following Reduction of Hazardous Inhalational Exposure: A PRM CT Case Report. [PDF]

open access: yesRespirol Case Rep
Serial parametric response mapping (PRM)‐computed tomography revealed dynamic changes in PRM‐functional small airway disease with occupational exposure, highlighting PRM's utility for detecting and monitoring small airway disease. ABSTRACT We report a case illustrating the role of parametric response mapping (PRM) in detecting and monitoring small ...
Lee YH, Im Y, Shin SH, Lee HY, Park HY.
europepmc   +2 more sources

Clinical Significance of Bronchodilator Responsiveness Evaluated by Forced Vital Capacity in COPD: SPIROMICS Cohort Analysis. [PDF]

open access: yes, 2019
ObjectiveBronchodilator responsiveness (BDR) is prevalent in COPD, but its clinical implications remain unclear. We explored the significance of BDR, defined by post-bronchodilator change in FEV1 (BDRFEV1) as a measure reflecting the change in flow and ...
Anderson, Wayne   +34 more
core   +2 more sources

Transforming acute exacerbations of chronic obstructive pulmonary disease (AECOPD) risk assessment: A multi‐algorithm machine learning approach for precise clinical phenotyping

open access: yesVIEW, EarlyView.
We addressed the clinical need for individualized early identification of AECOPD by analyzing a longitudinal cohort of 878 COPD patients (20072024) and benchmarking 91 algorithms, yielding an interpretable ensemble model (AECOPD‐RS). The model showed strong performance (C‐index 0.815; validation 1/3/5‐year AUCs 0.864/0.865/0.855), with SHAP/VIMP ...
Yiqun Dong   +5 more
wiley   +1 more source

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