Results 111 to 120 of about 213,364 (422)

Illuminating Immunity: A Systematic Review of Immune Cell Autofluorescence

Journal of Biophotonics, EarlyView.
ABSTRACT Immunophenotyping provides valuable prognostic and diagnostic information, but is technically complex and expensive. The assessment of autofluorescence is label‐free and provides complex information on cell identity. However, research on its application to immunophenotyping has been heterogenous.
Aline Knab, Caroline Giardina, Shane T. Grey, Ewa M. Goldys, Jared M. Campbell   +4 more
wiley   +1 more source

Role of Dual-Specificity Phosphatase 1 in Glucocorticoid-Driven Anti-inflammatory Responses

Frontiers in Immunology, 2019
Glucocorticoids (GCs) potently inhibit pro-inflammatory responses and are widely used for the treatment of inflammatory diseases, such as allergies, autoimmune disorders, and asthma. Dual-specificity phosphatase 1 (DUSP1), also known as mitogen-activated
Jessica Hoppstädter, Alaina J. Ammit, Alaina J. Ammit   +2 more
doaj   +1 more source

Epidemiology, genetics, and subtyping of preserved ratio impaired spirometry (PRISm) in COPDGene. [PDF]

, 2014
BackgroundPreserved Ratio Impaired Spirometry (PRISm), defined as a reduced FEV1 in the setting of a preserved FEV1/FVC ratio, is highly prevalent and is associated with increased respiratory symptoms, systemic inflammation, and mortality.
Beaty, Terri H, Castaldi, Peter J, Cho, Michael H, COPDGene Investigators, Crapo, James D, Curran-Everett, Douglas, Curtis, Jeffrey L, DeMeo, Dawn L, Han, MeiLan K, Hokanson, John E, Lynch, David A, Make, Barry J, Regan, Elizabeth A, Silverman, Edwin K, Wan, Emily S   +14 more
core   +2 more sources

Functional Pulmonary Imaging

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT The aging of the world population gave rise to an increased prevalence of many lung diseases, with chronic obstructive pulmonary disease now ranking as the third‐leading cause of death according to the World Health Organization. To diagnose lung disease, a thorough assessment of lung function is essential since it may reveal unique signatures ...
Agilo L. Kern, Filip Klimeš, Andreas Voskrebenzev, Hoen‐Oh Shin, Jens Vogel‐Claussen   +4 more
wiley   +1 more source

Effect of emphysema on AI software and human reader performance in lung nodule detection from low-dose chest CT

European Radiology Experimental
Background Emphysema influences the appearance of lung tissue in computed tomography (CT). We evaluated whether this affects lung nodule detection by artificial intelligence (AI) and human readers (HR).
Nikos Sourlos, GertJan Pelgrim, Hendrik Joost Wisselink, Xiaofei Yang, Gonda de Jonge, Mieneke Rook, Mathias Prokop, Grigory Sidorenkov, Marcel van Tuinen, Rozemarijn Vliegenthart, Peter M. A. van Ooijen   +10 more
doaj   +1 more source

Characteristics of phenotypes of elderly patients with asthma

Allergology International, 2016
Background: The characteristics of phenotypes of elderly patients with asthma are unknown. The aim of this study was to classify these phenotypes using lung function tests and images from high-resolution computed tomography (HRCT), and to identify ...
Hiroyuki Sano, Takashi Iwanaga, Osamu Nishiyama, Akiko Sano, Yuji Higashimoto, Katsuyuki Tomita, Yuji Tohda   +6 more
doaj   +1 more source

COPD Classification in CT Images Using a 3D Convolutional Neural Network [PDF]

arXiv, 2020
Chronic obstructive pulmonary disease (COPD) is a lung disease that is not fully reversible and one of the leading causes of morbidity and mortality in the world. Early detection and diagnosis of COPD can increase the survival rate and reduce the risk of COPD progression in patients.
arxiv  

Current concepts on the role of inflammation in COPD and lung cancer [PDF]

, 2009
Chronic obstructive pulmonary disease (COPD) and lung cancer are leading cause of death, and both are associated with cigarette smoke exposure. It has been shown that 50–70% of patients diagnosed with lung cancer suffer from COPD, and reduced lung ...
Abdel-Aziz, Adenuga, Barnes, Bonomi, Brock, Campisi, Cao, Chen, Edirisinghe, Fong, Gebel, Goswami, Gozuacik, Gridelli, Hogg, Hogg, Hongwei Yao, Houghton, Irfan Rahman, Ito, Kamlah, Kasahara, Lee, Liu, Liu, Mannino, Marwick, Michaud, Moghaddam, Morris, Nozik-Grayck, Parimon, Pilette, Rajendrasozhan, Reiman, Rossi, Saitoh, Scherz-Shouval, Senderowicz, Siafakas, Sun, Takizawa, Tomita, Tsuji, van der Strate, van Houwelingen, Voelkel, Yamamoto, Yang, Yang, Yao, Yue   +51 more
core   +1 more source

Magnetic Resonance Imaging in the Clinical Evaluation of Lung Disorders: Current Status and Future Prospects

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT The low proton density and high signal decay rate of pulmonary tissue have previously hampered the application of magnetic resonance imaging (MRI) in the clinical evaluation of lung disorders. With the continuing technical advances in scanners, coils, pulse sequences, and image postprocessing, pulmonary MRI can provide structural and ...
Linyu Wu, Chen Gao, Ting Wu, Ning Kong, Ziwei Zhang, Jie Li, Li Fan, Maosheng Xu   +7 more
wiley   +1 more source

Explaining Radiological Emphysema Subtypes with Unsupervised Texture Prototypes: MESA COPD Study [PDF]

arXiv, 2016
Pulmonary emphysema is traditionally subcategorized into three subtypes, which have distinct radiological appearances on computed tomography (CT) and can help with the diagnosis of chronic obstructive pulmonary disease (COPD). Automated texture-based quantification of emphysema subtypes has been successfully implemented via supervised learning of these
arxiv