Results 51 to 60 of about 1,302,502 (286)

Weighted Empirical Likelihood for Accelerated Life Model with Various Types of Censored Data

Stats
In analysis of survival data, the Accelerated Life Model (ALM) is one of the widely used semiparametric models, and we often encounter various types of censored survival data, such as right censored data, doubly censored data, interval censored data ...
Jian-Jian Ren, Yiming Lyu
doaj   +1 more source

Empirical likelihood confidence regions of the parameters in a partially single-index varying-coefficient model

Open Mathematics, 2019
In this paper, we investigate a partially single-index varying-coefficient model, and suggest two empirical log-likelihood ratio statistics for the unknown parameters in the model.
Xiang Xing, Liu Wanrong
doaj   +1 more source

Empirical likelihood inference for threshold autoregressive conditional heteroscedasticity model

Journal of Inequalities and Applications, 2021
This paper considers the parameter estimation problem of a first-order threshold autoregressive conditional heteroscedasticity model by using the empirical likelihood method.
Cuixin Peng, Zhiwen Zhao
doaj   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Estimation of Random Coefficient Autoregressive Model with Error in Covariates

Axioms
Measurement error is common in many statistical problems and has received considerable attention in various regression contexts. In this study, we consider the random coefficient autoregressive model with measurement error possibly present in covariates.
Xiaolei Zhang, Jin Chen, Qi Li
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Exploratory Analysis of ELP1 Expression in Whole Blood From Patients With Familial Dysautonomia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Familial dysautonomia (FD) is a hereditary neurodevelopmental disorder caused by aberrant splicing of the ELP1 gene, leading to a tissue‐specific reduction in ELP1 protein expression. Preclinical models indicate that increasing ELP1 levels can mitigate disease manifestations.
Alejandra González‐Duarte, Lucy Norcliffe‐Kaufmann, Maria Luisa Cotrina, Zenith Khan, Kaia Dalamo, Patricio Millar Vernetti, Matthew Lawless, Elisabetta Morini, Monica Salani, Marla Weetall, Jana Narasimhan, Agostino G. Rocha, Susan A. Slaugenhaupt, Horacio Kaufmann   +13 more
wiley   +1 more source

Empirical likelihood estimation in multivariate mixture models with repeated measurements

Statistical Theory and Related Fields, 2020
Multivariate mixtures are encountered in situations where the data are repeated or clustered measurements in the presence of heterogeneity among the observations with unknown proportions.
Yuejiao Fu, Yukun Liu, Hsiao-Hsuan Wang, Xiaogang Wang   +3 more
doaj   +1 more source

Jackknife Empirical Likelihood Inference for the Variance Residual Life Function

Revstat Statistical Journal, 2021
In life testing situations, the residual life time of a component which has survived t units of time is Xt = X −t|X > t. In this paper, we give a central limit theorem result for the estimator of Var(Xt), the variance residual life(VRL) function.
Vali Zardasht
doaj   +1 more source

Functional Connectivity Linked to Cognitive Recovery After Minor Stroke

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Patients with minor stroke exhibit slowed processing speed and generalized alterations in functional connectivity involving frontoparietal cortex (FPC). The pattern of connectivity evolves over time. In this study, we examine the relationship of functional connectivity patterns to cognitive performance, to determine ...
Vrishab Commuri, Isabella Dallasta, Ciaran Stone, Sophia Girgenti, Neda Gould, Rafael H. Llinas, Jonathan Z. Simon, Elisabeth Breese Marsh   +7 more
wiley   +1 more source