Results 61 to 70 of about 29,567,174 (335)

Empirical Study of the GARCH model with Rational Errors

, 2013
We use the GARCH model with a fat-tailed error distribution described by a rational function and apply it for the stock price data on the Tokyo Stock Exchange. To determine the model parameters we perform the Bayesian inference to the model. The Bayesian
Chen, Ting Ting, Takaishi, Tetsuya
core   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

A Generalized Empirical Model for Velocity Deficit and Turbulent Intensity in Tidal Turbine Wake Accounting for the Effect of Rotor-Diameter-to-Depth Ratio

Energies
Commercial scale tidal stream turbines (TST) are expected to be deployed in shallow water where the depth varies from 1.5 to 3 turbine diameters. In this study, numerical simulation is conducted at realistic hydrodynamic conditions of potential tidal ...
Kabir Bashir Shariff, Sylvain S. Guillou
doaj   +1 more source

Fast and Accurate Temperature-Dependent Current Modeling of HBTs Using the Dimension Reduction Method

IEEE Access, 2019
Empirical models have been widely and successfully used in device modeling in the past few decades. However, they are becoming increasingly intricate to accurately capture the complex thermal effects in semiconductor devices.
Wenrui Hu, Andong Huang, Haorui Luo, Yong-Xin Guo   +3 more
doaj   +1 more source

Estimation of Potential Evapotranspiration in the Yellow River Basin Using Machine Learning Models

Atmosphere, 2022
Potential evapotranspiration (PET) is an important input variable of many ecohydrological models, but commonly used empirical models usually input numerous meteorological factors.
Jie Liu, Kunxia Yu, Peng Li, Lu Jia, Xiaoming Zhang, Zhi Yang, Yang Zhao   +6 more
doaj   +1 more source

Model atmospheres of chemically peculiar stars: Self-consistent empirical stratified model of HD24712

, 2009
High-resolution spectra of some chemically peculiar stars clearly demonstrate the presence of strong abundance gradients in their atmospheres. However, these inhomogeneities are usually ignored in the standard scheme of model atmosphere calculations ...
Alecian, Babel, Bard, Bard, Black, Blackwell, Blackwell, Blanco, Campos, D. Shulyak, Fleurier, Garz, Goncharsky, Hauck, Hauschildt, Hui-Bon-Hoa, Khan, Khan, Kochukhov, Kochukhov, Kochukhov, Kochukhov, Kochukhov, Kupka, L. Mashonkina, Lueftinger, Lundberg, Mashonkina, Mashonkina, Mashonkina, Mashonkina, Michaud, Nieuwenhuijzen, O. Kochukhov, Piskunov, Piskunov, Piskunov, Raassen, Ryabchikova, Ryabchikova, Ryabchikova, Ryabchikova, Rybicki, Rybicki, Seaton, Smith, Smith, Smith, Smith, Stepanov, T. Ryabchikova, Vogt, Warner, Weiss, Wolff   +54 more
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

An Experimental Direct Model for the Sky Temperature Evaluation in the Mediterranean Area: A Preliminary Investigation

Energies
Since the beginning of the 20th century, many studies have focused on the possibility of considering the sky as a body characterized by an apparent temperature, and several correlations to quantify the apparent sky temperature have been proposed. However,
Edoardo De Cristo, Luca Evangelisti, Claudia Guattari, Roberto De Lieto Vollaro   +3 more
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

FEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman, Katarzyna Stapor, Leszek Konieczny, Krzysztof Gądek, Piotr Nowakowski   +4 more
wiley   +1 more source