Empirical Evidence of Large-Scale Diversity in API Usage of Object-Oriented Software [PDF]
In this paper, we study how object-oriented classes are used across thousands of software packages. We concentrate on "usage diversity'", defined as the different statically observable combinations of methods called on the same object.
Baudry, Benoit +2 more
core +5 more sources
SMS-Builder: An adaptive software tool for building systematic mapping studies
A Systematic Mapping Study is an instrument frequently used to carry out a search process, identification, and classification of studies in different fields.
Christian A. Candela-Uribe +6 more
doaj +1 more source
Complementarity of Long‐Reads and Optical Mapping in Parkinson's Disease for Structural Variants
ABSTRACT Objective Long‐read sequencing and optical genome mapping technologies have the ability to detect large and complex structural variants. This has led to the discovery of novel pathogenic variants in neurodegenerative movement disorders. Thus, we aimed to systematically compare the SV detection capabilities of OGM and ONT in Parkinson's disease.
André Fienemann +17 more
wiley +1 more source
Enablers and Impediments for Collaborative Research in Software Testing: An Empirical Exploration
When it comes to industrial organizations, current collaboration efforts in software engineering research are very often kept in-house, depriving these organizations off the skills necessary to build independent collaborative research. The current trend,
Causevic, Adnan, Enoiu, Eduard Paul
core +1 more source
Software engineering has traditionally focused on the semantic and notational aspects of domain model understandability, overlooking the cognitive factors involved in this process.
Santiago Melia +2 more
doaj +1 more source
Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz +3 more
wiley +1 more source
New ideas and emerging research: evaluating prediction system accuracy [PDF]
BACKGROUND: Prediction e.g. of project cost is an important concern in software engineering. PROBLEM: Although many empirical validations of software engineering prediction systems have been published, no one approach dominates and sense-making of ...
Shepperd, M
core
RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu +21 more
wiley +1 more source
Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD
ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin +11 more
wiley +1 more source
Mining Software Repair Models for Reasoning on the Search Space of Automated Program Fixing
This paper is about understanding the nature of bug fixing by analyzing thousands of bug fix transactions of software repositories. It then places this learned knowledge in the context of automated program repair.
Martinez, Matias, Monperrus, Martin
core +1 more source

