Results 51 to 60 of about 778,544 (340)

Empirical Evidence of Large-Scale Diversity in API Usage of Object-Oriented Software [PDF]

open access: yes, 2013
In this paper, we study how object-oriented classes are used across thousands of software packages. We concentrate on "usage diversity'", defined as the different statically observable combinations of methods called on the same object.
Baudry, Benoit   +2 more
core   +5 more sources

SMS-Builder: An adaptive software tool for building systematic mapping studies

open access: yesSoftwareX, 2022
A Systematic Mapping Study is an instrument frequently used to carry out a search process, identification, and classification of studies in different fields.
Christian A. Candela-Uribe   +6 more
doaj   +1 more source

Complementarity of Long‐Reads and Optical Mapping in Parkinson's Disease for Structural Variants

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Long‐read sequencing and optical genome mapping technologies have the ability to detect large and complex structural variants. This has led to the discovery of novel pathogenic variants in neurodegenerative movement disorders. Thus, we aimed to systematically compare the SV detection capabilities of OGM and ONT in Parkinson's disease.
André Fienemann   +17 more
wiley   +1 more source

Enablers and Impediments for Collaborative Research in Software Testing: An Empirical Exploration

open access: yes, 2014
When it comes to industrial organizations, current collaboration efforts in software engineering research are very often kept in-house, depriving these organizations off the skills necessary to build independent collaborative research. The current trend,
Causevic, Adnan, Enoiu, Eduard Paul
core   +1 more source

The Effect of Developers’ General Intelligence on the Understandability of Domain Models: An Empirical Study

open access: yesIEEE Access, 2023
Software engineering has traditionally focused on the semantic and notational aspects of domain model understandability, overlooking the cognitive factors involved in this process.
Santiago Melia   +2 more
doaj   +1 more source

Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz   +3 more
wiley   +1 more source

New ideas and emerging research: evaluating prediction system accuracy [PDF]

open access: yes, 2011
BACKGROUND: Prediction e.g. of project cost is an important concern in software engineering. PROBLEM: Although many empirical validations of software engineering prediction systems have been published, no one approach dominates and sense-making of ...
Shepperd, M
core  

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu   +21 more
wiley   +1 more source

Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin   +11 more
wiley   +1 more source

Mining Software Repair Models for Reasoning on the Search Space of Automated Program Fixing

open access: yes, 2013
This paper is about understanding the nature of bug fixing by analyzing thousands of bug fix transactions of software repositories. It then places this learned knowledge in the context of automated program repair.
Martinez, Matias, Monperrus, Martin
core   +1 more source

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