Introverted Metaphysics: How We Get Our Grip on the Ultimate Nature of Objects, Properties, and Causation [PDF]
This paper pulls together three debates fundamental in metaphysics and proposes a novel unified approach to them. The three debates are (i) between bundle theory and substrate theory about the nature of objects, (ii) dispositionalism and categoricalism ...
Kriegel, Uriah
core
A 73‐Year‐Old Man With Several Years of Difficulty Climbing Stairs and Frequent Tripping
ABSTRACT A 73‐year‐old man presented with progressive weakness and atrophy predominantly affecting the distal finger flexors and quadriceps muscles. Electrophysiological studies demonstrated mixed myogenic and neurogenic features. Muscle MRI showed inflammatory changes, and muscle biopsy revealed granulomatous myositis with histologic features ...
Mehmet Can Sari +3 more
wiley +1 more source
Do We Need a Scientific Revolution? [PDF]
Many see modern science as having serious defects, intellectual, social, moral. Few see this as having anything to do with the philosophy of science.
Maxwell, N
core
Epistemological Realism and Onto-Relations [PDF]
The traditional concept of knowledge is a justified true belief. The bulk of contemporary epistemology has focused primarily on that task of justification. Truth seems to be a quite obvious criterion—does the belief in question correspond to reality?
Andrews, Max Lewis Edward
core +1 more source
Complementarity of Long‐Reads and Optical Mapping in Parkinson's Disease for Structural Variants
ABSTRACT Objective Long‐read sequencing and optical genome mapping technologies have the ability to detect large and complex structural variants. This has led to the discovery of novel pathogenic variants in neurodegenerative movement disorders. Thus, we aimed to systematically compare the SV detection capabilities of OGM and ONT in Parkinson's disease.
André Fienemann +17 more
wiley +1 more source
The Disastrous Implications of the 'English' View of Rationality in a Social World [PDF]
Van Fraassen (2007, 2017) consistently uses the English view of rationality to parry criticisms from scientific realists. I assume for the sake of argument that the English view of rationality is tenable, and then argue that it has disastrous ...
Park, Seungbae
core +2 more sources
Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz +3 more
wiley +1 more source
The Excellency of Theology: A Critique of Robert K. Merton\'s \"Puritan Thesis,\" with Reference to the Works of Robert Boyle [PDF]
Robert K. Merton's "Puritan Thesis" asserts a direct correlation between Puritan theological beliefs and participation in natural philosophy (what today would be known as science).
Patton, Elizabeth
core +1 more source
Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS
ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi +8 more
wiley +1 more source
Enforceable promises discourage lying, cheating, and stealing. Contracts that embody such promises shape institutions, distribute power, and organize markets.
Gelpern, Anna
core +1 more source

