Results 91 to 100 of about 113,561 (293)

Introverted Metaphysics: How We Get Our Grip on the Ultimate Nature of Objects, Properties, and Causation [PDF]

open access: yes, 2019
This paper pulls together three debates fundamental in metaphysics and proposes a novel unified approach to them. The three debates are (i) between bundle theory and substrate theory about the nature of objects, (ii) dispositionalism and categoricalism ...
Kriegel, Uriah
core  

A 73‐Year‐Old Man With Several Years of Difficulty Climbing Stairs and Frequent Tripping

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT A 73‐year‐old man presented with progressive weakness and atrophy predominantly affecting the distal finger flexors and quadriceps muscles. Electrophysiological studies demonstrated mixed myogenic and neurogenic features. Muscle MRI showed inflammatory changes, and muscle biopsy revealed granulomatous myositis with histologic features ...
Mehmet Can Sari   +3 more
wiley   +1 more source

Do We Need a Scientific Revolution? [PDF]

open access: yes
Many see modern science as having serious defects, intellectual, social, moral. Few see this as having anything to do with the philosophy of science.
Maxwell, N
core  

Epistemological Realism and Onto-Relations [PDF]

open access: yes, 2014
The traditional concept of knowledge is a justified true belief. The bulk of contemporary epistemology has focused primarily on that task of justification. Truth seems to be a quite obvious criterion—does the belief in question correspond to reality?
Andrews, Max Lewis Edward
core   +1 more source

Complementarity of Long‐Reads and Optical Mapping in Parkinson's Disease for Structural Variants

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Long‐read sequencing and optical genome mapping technologies have the ability to detect large and complex structural variants. This has led to the discovery of novel pathogenic variants in neurodegenerative movement disorders. Thus, we aimed to systematically compare the SV detection capabilities of OGM and ONT in Parkinson's disease.
André Fienemann   +17 more
wiley   +1 more source

The Disastrous Implications of the 'English' View of Rationality in a Social World [PDF]

open access: yes, 2018
Van Fraassen (2007, 2017) consistently uses the English view of rationality to parry criticisms from scientific realists. I assume for the sake of argument that the English view of rationality is tenable, and then argue that it has disastrous ...
Park, Seungbae
core   +2 more sources

Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz   +3 more
wiley   +1 more source

The Excellency of Theology: A Critique of Robert K. Merton\'s \"Puritan Thesis,\" with Reference to the Works of Robert Boyle [PDF]

open access: yes, 2012
Robert K. Merton's "Puritan Thesis" asserts a direct correlation between Puritan theological beliefs and participation in natural philosophy (what today would be known as science).
Patton, Elizabeth
core   +1 more source

Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi   +8 more
wiley   +1 more source

Commentary [PDF]

open access: yes, 2009
Enforceable promises discourage lying, cheating, and stealing. Contracts that embody such promises shape institutions, distribute power, and organize markets.
Gelpern, Anna
core   +1 more source

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