Results 81 to 90 of about 8,251,496 (287)

Neoclassical growth models and the optimum rate of population growth (with applications to underdeveloped countries) [PDF]

open access: yes, 1970
For more about the East-West Center, see http://www.eastwestcenter.org/Among economists who are also interested in demography, there is a respectable tradition of analysis revolving around the concept of a static optimum population. The work of W.
Crouch, Robert L.   +1 more
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Population research in the Pacific Islands : a case study and some reflections [PDF]

open access: yes, 1971
For more about the East-West Center, see http://www.eastwestcenter.org/This paper outlines the aims and methods (rather than the results) of a study of population movement undertaken in the British Solomon Islands Protectorate between October 1965 and ...
East-West Population Institute   +1 more
core   +1 more source

CORRELATION-REGRESSION MODEL OF MIGRATION FLOWS OF EMPLOYED RURAL POPULATION IN SARATOV REGION, RUSSIAN FEDERATION [PDF]

open access: yesScientific Papers Series : Management, Economic Engineering in Agriculture and Rural Development, 2021
The problems of the migration outflow of the able-bodied population in the Russian Federation are reflected on the example of the Volga Federal District, which is leading in terms of these indicators. For a monographic study from the group of rural areas
Sergey Germanovich GLUKHOV   +2 more
doaj  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Components of regional population growth, 1986-2001 [PDF]

open access: yes, 2004
The vitality of a region is frequently assessed by looking at its population growth pattern. This is seen as being linked to its economic and social vibrancy.
Pool, Ian   +2 more
core  

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Population Bulletin, VOL. 75, NO. 1

open access: yes, 2021
This is an overview of important demographic processes including fertility, mortality, and migration, and their effects on population growth, decline, and composition. The authors describe changes in the geographic distribution of the world’s population,
Mather, Mark   +2 more
core  

THE INTERNATIONAL MIGRATION AND ITS EFFECTS AT THE EUROPEAN AND NATIONAL LEVEL [PDF]

open access: yesAnnals of the University of Craiova: Economic Sciences Series, 2019
In the following, the author proposes to analyze the context of the workforce migration, as well as the remittances, a phenomenon occurring in parallel with the population migration.
Flavia Andreea Murtaza
doaj  

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