Results 101 to 110 of about 685,355 (306)

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Budgetary participation and its impact on individual performance

open access: yesTourism and Hospitality Management, 2018
Purpose – The study examines the influence of budgeting participation on employee performance. The mediating variables are pride in membership (PIM) and job satisfaction (JS).
Yuliansyah Yuliansyah   +3 more
doaj   +1 more source

Utilization of Tax Incentives for Retirement Saving: An Update [PDF]

open access: yes, 2006
[From Preface] This Congressional Budget Office background paper updates CBO’s Utilization of Tax Incentives for Retirement Saving (August 2003). That paper examined participation rates and contributions to employment-based retirement plans, individual ...
U.S. Congressional Budget Office
core   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Employer Matching and 401(k) Saving: Evidence from the Health and Retirement Study [PDF]

open access: yes
Employer matching of employee 401(k) contributions can provide a powerful incentive to save for retirement and is a key component in pension-plan design in the United States.
Anil Kumar, Gary V. Engelhardt
core  

Pengaruh Budgeting Participation terhadap Employee Performance pada Sektor Jasa di Surabaya [PDF]

open access: yes, 2013
Memasuki era perdagangan bebas sekarang ini, industri jasa telah mengalami perkembangan ke arah modern dimana persaingan yang terjadi semakin kompetitif.
Pribadi, S. A. (Stephani)
core  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Budgetary participation and performance mediated by work satisfaction and engagement at Timor-Leste

open access: yesContabilidad y Negocios: Revista del Departamento Académico de Ciencias Administrativas
Budgetary participation is paramount in organizational management since it has a direct impact on operations efficacy and the organization success. At Timor-Leste, where managerial practices are still being developed, budgetary participation can be ...
Marta Guterres   +1 more
doaj   +1 more source

BLS Spotlight on Statistics: Employer-Sponsored Healthcare Coverage Across Wage Groups [PDF]

open access: yes, 2017
[Excerpt] In March of 2016, a little more than half of all private industry employees participated in employer-sponsored healthcare benefit plans. However, workers earning different wages often have markedly different experiences with healthcare benefits.
Wile, David
core   +1 more source

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