Results 121 to 130 of about 1,437,204 (363)

Diagnostic yield and complications of thoracic ultrasound-guided biopsy performed by pulmonologists

open access: yesMonaldi Archives for Chest Disease
Interventional pulmonology is a growing field in India, and adding thoracic ultrasound (TUS)-guided lung biopsy can be useful for interventional pulmonologists. This study evaluated whether TUS-guided lung biopsy performed by pulmonologists, without the
Rahul Kumar   +7 more
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

Awareness, knowledge, and attitudes towards Developmental Language Disorders (DLD) among public university Students in Bangladesh

open access: yesJournal of Child Language Acquisition and Development
Background: Developmental Language Disorder (DLD) affects communication and learning, yet remains less identified throughout South Asia. The study investigated public university students’ awareness, factual knowledge and attitudes towards DLD in ...
Shahriar Kabir Fahim   +2 more
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

La toma de decisiones de los hogares de Venezuela

open access: yesRevista de Economía Institucional, 2008
Este artículo analiza quién toma las decisiones en los hogares y los factores que intervienen en ello. Esta investigación se realizó en Venezuela, donde se preguntó a las mujeres cómo tomaban las decisiones de sus hogares en cuatro áreas.
Pareena G. Lawrence, Marakah Mancini
doaj  

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

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