Results 121 to 130 of about 1,222,613 (317)
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Oregon occupational employment projections
Converted from Excel.This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.Mode of access: Internet from the ...
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Harmonising French and German administrative DADS-EDP and SIAB data
Journal for Labour Market ResearchAdministrative data are increasingly used in social science research, including for studying the labour market consequences of motherhood. Yet despite the growing use of such data within countries, cross-national comparative research remains limited ...
Andreas Filser +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Oregon industry employment projections
Converted from Excel.This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.Mode of access: Internet from the ...
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State Employment Relations Board annual report
, 2004 Annual; Electronic coverage as of Jan. 17, 2007: 2004-; Description based on: 2004; title from PDF cover (viewed on Jan. 17, 2007).; Vol.
Ohio. State Employment Relations Board.
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Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Employment Bulletin, April 2020
, 2020 The Employment Bulletin contains statistics on unemployment, open job vacancies, and employment service developments. Statistics updates on a monthly basis.
Kuusela, Kaisa-Mari
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