Results 211 to 220 of about 3,888,750 (341)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Development of a clinical tool to identify patients with early inflammatory arthritis at high risk of employment loss: analysis from the National Early Inflammatory Arthritis Audit. [PDF]

Rheumatol Adv Pract
Alveyn E, Bechman K, Adas M, Amlani-Hatcher P, Dey M, Gallagher S, Gibson M, Jones B, Mehta D, Norton S, Price E, Russell M, Walker-Bone K, MacPhie E, Galloway J.   +14 more
europepmc   +1 more source

Graduate employability and employment

, 2023
openaire   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Labour market patterns among women and men following the uptake of their first parental leave benefit in Sweden. [PDF]

Sci Rep
Virtanen M, Gémes K, Farrants K, Bergström J, Gustafsson N, Peutere L, Mittendorfer-Rutz E, Alexanderson K.   +7 more
europepmc   +1 more source

Women’s employment and fertility in Korea [PDF]

Syngjoo Choi, Sunyu Ham, Y. Tony Yang, Jon Pareliussen   +3 more
openalex   +1 more source

Pandemic Restrictions Are Over: An Overview of Changes in the Main Economic Indicators of Enterprises. Part 1. Production, Prices, Employment, Financial Position of Enterprise s and Profitability

, 2022
А. Batyaeva
openalex   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

An inquiry into labor conditions across key rural sectors in Africa. [PDF]

PLoS One
Nzira JE, Parlasca MC, Qaim M.
europepmc   +1 more source

The Significance of the Implied Mutual Duty of Trust and Confidence in the Employment Relationship

, 2009
Katie McDermott
openalex   +2 more sources