Results 71 to 80 of about 623,517 (267)
Управление, 2017 Legal regulation of national qualifications systems in countries-participants of the CIS, EAEU and the BRICS and the prospects for cooperation in the field of free labor-force movement within these unions, connect with the solution of problems of mutual ...
L. A. Sokolova +2 more
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Employers' preferences for migrant employment and informal employment
The F2F sectors in Europe have become increasingly reliant on migrant labour. At the same time, agriculture and other low-paid, low-skilled sectors are characterised by higher levels of informality than the economy as a whole. In DignityFIRM, we aimed to investigate employers’ strategies regarding recruitment and hiring, and whether their decisions to ...
Fihel, Agnieszka +2 more
openaire +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Soldiers’ employment attitude and employability: An exploratory study
Journal of Industrial Engineering and Management, 2015 Purpose: Nowadays it is very difficult for Chinese retired soldiers to find proper jobs, and the primary reason is the significant gap between job requirements and soldiers owned job skills. Therefore, it is very important to improve the soldiers’ job skills and enhance their understanding of employment.
Gao, Peng, Yuan, Lunqu
openaire +6 more sources
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
RSF: The Russell Sage Foundation Journal of the Social Sciences, 2019 This article uses the metaphor of a social contract to review the evolution of American unions and their effects— especially in the variations in their quality—on firm employment strategies and performance, takes stock of the current state of unions and ...
Thomas A. Kochan, William T. Kimball
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source