Results 101 to 110 of about 644,032 (327)
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Homologous expression and purification of human HAX‐1 for structural studies
FEBS Open Bio, EarlyView.This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley +1 more source
Designing container shipping network under changing demand and freight rates
Transport, 2010 This paper focuses on the optimization of container shipping network and its operations under changing cargo demand and freight rates. The problem is formulated as a mixed integer non-linear programming problem (MINP) with an objective of maximizing the ...
Chao Chen, Qingcheng Zeng
doaj +3 more sources
FEBS Open Bio, EarlyView.The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan +6 more
wiley +1 more source
Beers, kaffi, and Schnaps : different grammatical options for 'restaurant talk' coercions in three Germanic languages [PDF]
, 2009 This paper discusses constructions like “We’ll have two beers and a coffee.” that are typically used for beverage orders in restaurant contexts. We compare the behaviour of nouns in these constructions in three Germanic languages, English, Icelandic, and
Maling, Joan, Wiese, Heike
core
Jurnal Adiguna Maritim IndonesiaPenelitian ini membahas tentang Sistem Pengembalian dan Pengambilan Container Empty di Depo PT. Tanto Intim Line Cabang Medan Belawan yang dilakukan oleh ekspedisi muatan kapal laut (EMKL). Dalam penelitian ini, penulis menggunakan dua metode yaitu riset
Husna Chairani Pane +2 more
semanticscholar +1 more source
Autophagosome marker, LC3, is released extracellularly via several distinct pathways
FEBS Open Bio, EarlyView.This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito +3 more
wiley +1 more source
Chemical Engineering Transactions, 2018 This article presents a model of a storage container of linear crystallizer. On the base of this model two independent control system of storage containers filling in a uranyl nitrate crystallization process were suggested.
Aleksandr O. Pletnev +5 more
doaj +1 more source
FEBS Open Bio, EarlyView.Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava +3 more
wiley +1 more source
Scaling in a general class of critical random Boolean networks
, 2006 We derive analytically the scaling behavior in the thermodynamic limit of the number of nonfrozen and relevant nodes in the most general class of critical Kauffman networks for any number of inputs per node, and for any choice of the probability ...
Drossel, Barbara, Mihaljev, Tamara
core +1 more source