Results 111 to 120 of about 644,032 (327)

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Generating scenarios for simulation and optimization of container terminal logistics

open access: yes, 2016
This paper introduces an approach for generating scenarios of sea port container terminals. A scenario consists of arrivals of deep sea vessels, feeder ships, trains, and trucks together with lists of containers to be loaded and unloaded.
Hartmann, Sönke
core  

CHIPS Science Investigation: Exploring the Interstellar Medium [PDF]

open access: yes, 2003
This booklet describes the interstellar medium and the local bubble that is being studied by NASA’s Cosmic Hot Interstellar Plasma Spectrometer (CHIPS) satellite.

core  

Further applications of the Container Method

open access: yes, 2016
Recently, Balogh--Morris--Samotij and Saxton--Thomason proved that hypergraphs satisfying some natural conditions have only few independent sets. Their main results already have several applications.
Balogh, Jozsef, Wagner, Adam Zsolt
core   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

Spherical tank gauge Patent [PDF]

open access: yes, 1967
Gauge for measuring quantity of liquid in spherical tank in reduced ...
Smith, H. A.
core   +1 more source

Olink Proteomics Analysis Reveals Heterogeneous Responses to FcRn Blockade in Anti‐AChR Antibody‐Positive Myasthenia Gravis: FGF‐19 as a Novel Biomarker

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to systematically observe the clinical manifestations, immune cell subsets, and dynamic changes in serological indicators in patients with myasthenia gravis (MG) before and after efgartigimod (EFG) treatment. Methods We analyzed the baseline data, laboratory parameters, and lymphocyte subset proportions in MG ...
Tiancheng Luo   +9 more
wiley   +1 more source

Clinical Practice Guideline for Evaluation and Management of Peripheral Nervous System Manifestations in Sjögren's Disease

open access: yesArthritis Care &Research, Accepted Article.
Objectives Sjögren's disease is an autoimmune disorder that can impact multiple organ systems, including the peripheral nervous system (PNS). PNS manifestations, which can exist concurrently, include mononeuropathies, polyneuropathies, and autonomic nervous system neuropathies. To help patients and providers in the decision‐making process, we developed
Anahita Deboo   +19 more
wiley   +1 more source

Containership Traffic Optimization on Feeder Shipping Line

open access: yesTransport and Telecommunication, 2016
This article is devoted to feeder containership traffic optimization on the trunk and feeder shipping lines. The optimization is fulfilled in case of the necessity of laden containers delivery between fixed pairs of ports as well as in case of the ...
Drozhzhyn Oleksii
doaj   +1 more source

Home - About - Disclaimer - Privacy