Results 61 to 70 of about 644,032 (327)
Molecular bases of circadian magnesium rhythms across eukaryotes
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Empty Container Management in the Benelux Waterways [PDF]
The scientific contribution of this paper is the development of a model for empty container management in the hinterlands of the ports of Antwerp and Rotterdam.
Limbourg, Sabine, Salmon, Frédéric
core
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
System for creating on site, remote from a sterile environment, parenteral solutions [PDF]
The present invention provides a system and method for creating on site, remote from a sterile environment, parenteral solutions in large volume parenteral containers for intravenous administration to a patient. In an embodiment, this system comprises an
Bindokas, Al +6 more
core +1 more source
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
Design and Analysis of a Lightweight Composite Shipping Container Made of Carbon Fiber Laminates
The literature indicates that a 20% reduction in the weight of empty 40-foot shipping containers would result in $28 billion of fuel savings, along with a 3.6 exajoule reduction in the energy demand over containers’ 15-year lifetime. Decreasing the
Turkay Yildiz
doaj +1 more source
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
Generating Permutations with Restricted Containers [PDF]
We investigate a generalization of stacks that we call $\mathcal{C}$-machines. We show how this viewpoint rapidly leads to functional equations for the classes of permutations that $\mathcal{C}$-machines generate, and how these systems of functional ...
Albert, Michael H. +4 more
core +3 more sources
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Empty container reposition using max-min review system: Simulation approach
Global economic conditions and differences in the ability and economic competitiveness of each country cause an imbalance between exports and imports.
Adi Budipriyanto +2 more
semanticscholar +1 more source

