Results 71 to 80 of about 644,032 (327)

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

An Improved Large Neighborhood Search Algorithm for the Comprehensive Container Drayage Problem with Diverse Transport Requests

open access: yesApplied Sciences
Container drayage, as a pivotal element of door-to-door intermodal transportation, has garnered increasing attention due to its significant influence on container logistics costs.
Xuhui Yu, Cong He
doaj   +1 more source

Insecticidal Activity of 28 Essential Oils and a Commercial Product Containing Cinnamomum cassia Bark Essential Oil against Sitophilus zeamais Motschulsky

open access: yesInsects, 2020
Maize weevils, Sitophilus zeamais, are stored product pests mostly found in warm and humid regions around the globe. In the present study, acute toxicity via contact and residual bioassay and fumigant bioassay of 28 essential oils as well as their ...
Yunho Yang   +2 more
doaj   +1 more source

Double-Cycling AGV Scheduling Considering Uncertain Crane Operational Time at Container Terminals

open access: yesApplied Sciences, 2022
Container terminals (CTs) play an important role in the modern logistics and transportation industry. The utilization of automated guided vehicles (AGVs) can be effectively facilitated by reducing their empty running.
Hongchang Zhang   +3 more
doaj   +1 more source

Better bitmap performance with Roaring bitmaps [PDF]

open access: yes, 2016
Bitmap indexes are commonly used in databases and search engines. By exploiting bit-level parallelism, they can significantly accelerate queries. However, they can use much memory, and thus we might prefer compressed bitmap indexes.
Beyer   +10 more
core   +2 more sources

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

Impact of the COVID-19 Pandemic Disruptions on Container Transport

open access: yesEngineering Management in Production and Services, 2022
The COVID-19 pandemic caused unprecedented disruptions in the global economy, and container transport as a predominant means of the goods flow in global supply chains.
Kuźmicz Katarzyna Anna
doaj   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

Buffer Capacity Computation for Throughput Constrained Streaming Applications with Data-Dependent Inter-Task Communication [PDF]

open access: yes, 2008
Streaming applications are often implemented as task graphs, in which data is communicated from task to task over buffers. Currently, techniques exist to compute buffer capacities that guarantee satisfaction of the throughput constraint if the amount of ...
Bekooij, Marco J.G.   +2 more
core   +2 more sources

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

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