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A Synovium‐on‐Chip Platform to Study Multicellular Interactions in Arthritis

open access: yesAdvanced Healthcare Materials, EarlyView.
The Synovium‐on‐Chip comprises a thin microporous PDMS membrane to support co‐culture of fibroblast‐like synoviocytes (FLS), THP‐1‐derived macrophages, and endothelial cells, enabling real‐time analysis of synovial‐vascular interactions. FLS migration through the pores drives endothelial remodeling, while TNF‐α stimulation induces robust inflammatory ...
Laurens R. Spoelstra   +8 more
wiley   +1 more source

ON-LINE SCHEDULING OF EMPTY CONTAINERS [PDF]

open access: possibleAsia-Pacific Journal of Operational Research, 2012
This paper considers the empty container repositioning problem in an on-line scheduling setting. This optimization problem arising from container transportation management aims to balance empty containers distribution among transportation sites so as to minimize the total operating cost of loaded container shipping, empty container allocation and ...
LELE ZHANG, ANDREW WIRTH
openaire   +2 more sources

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