Results 131 to 140 of about 67,091 (268)

Nanobody‐Conjugated Theranostic Prodrug Targeting αvβ3 Integrin Enables Precision Cancer Therapy With Real‐Time Imaging

open access: yesAdvanced Healthcare Materials, EarlyView.
The image shows a schematic form a nanobody‐conjugated theranostic prodrug (NBD) platform targeting tumor‐associated αvβ3 integrin. The NBD system integrates selective nanobody‐mediated tumor recognition, glutathione‐responsive disulfide cleavage for doxorubicin release, and aza‐BODIPY‐based near‐infrared fluorescence for real‐time imaging.
Sanu Karan   +13 more
wiley   +1 more source

Kernkraftwerke Lippe-Ems (KLE). Bericht ueber das Geschaeftsjahr 1997

open access: yes, 1998
The Kernkraftwerke Lippe-Ems GmbH (KLE) is the operator of the Emsland reactor station at Lingen (Ems), equipped with a 1300 MW PWR. The partners of KLE are VEW ENERGIE, PreussenElektra, and RWE Energie.
Kernkraftwerk Lippe-Ems GmbH (KLE), Lingen (Germany)
core  

One‐Step Microfluidic Manufactured Fucose‐Decorated Sweetosomes Choose the Time and the Road for Their Intracellular Journey to Cancer Treatment

open access: yesAdvanced Healthcare Materials, EarlyView.
Sweetosomes, a new class of fucose‐decorated liposomes, are developed via a one‐step microfluidic process without surface chemistry. This study elucidates their main caveolae‐mediated entry and distinct endosomal trafficking. These nanostructures demonstrate superior endosomal escape, organelle acidity modulation, and prolonged plasma persistence ...
Mattia Tiboni   +13 more
wiley   +1 more source

Dynamics of Intra-EMS Interest Rate Linkages [PDF]

open access: yes
interest rates, long memory, error ...
Christopher F Baum, John Barkoulas
core  

Medical convoy: interfacility transfer of hospitalized patients during Hajj season 2019

open access: yesSaudi Journal of Emergency Medicine
Background: Millions of Muslims gather annually in Makkah, Saudi Arabia, for pilgrimage (the Hajj). Some medical conditions need specialized care involving transfer outside the hospital.
Anas A. Khan   +11 more
doaj   +1 more source

Extracellular Vesicles Modulation by an Adiponectin Receptor Agonist Provides Cardioprotection for Myocardial Ischemic Injury

open access: yesAdvanced Healthcare Materials, EarlyView.
This study demonstrates that ALY688, a drug mimicking the heart‐protective hormone adiponectin, reduces myocardial ischemia injury. ALY688 increases the production of extracellular vesicles, which carry protective cargo including adiponectin itself.
Jialing Tang   +13 more
wiley   +1 more source

The EMS Crisis of the 1990s: Parallels with the present crisis? CEPS Working Document No. 393, 28 March 2014 [PDF]

open access: yes, 2014
The EMS crisis of the 1990s illustrated the importance of a lack of confidence in price or exchange rate stability, whereas the present crisis illustrates the importance of a lack of confidence in fiscal sustainability.
Gros, Daniel.
core  

Sátira de Kaliyuga (Kaliviḍambanam)

open access: yesEstudios de Asia y África, 2008
Nīlakaṇṭha Dīkṣita nació en la segunda mitad del siglo XVII enel seno del famoso linaje de brahmines eruditos del sur de la India, los Dīkṣita, al que también perteneció el gran Appayya Dīkṣita, su abuelo y muy probablemente su primer mentor. Durante su época productiva, Nīlakaṇṭha desempeñó diversos cargos en la corte de la dinastía de los reyes ...
openaire   +2 more sources

Tuning the Testicular Microenvironment for Enhancing Human Sertoli Cells Maturation and Functionality In Vitro

open access: yesAdvanced Healthcare Materials, EarlyView.
An in vitro testicular model is developed by generating connective tissue equivalents from human dermal fibroblast‐derived microtissues and coupling them with human Sertoli cells or human Sertoli cell spheroids. This engineered microenvironment supports Sertoli cell maturation and functionality, providing a promising platform for studying human ...
Annachiara Scalzone   +4 more
wiley   +1 more source

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