Results 261 to 270 of about 338,860 (400)

EMT-Regulome: a database for EMT-related regulatory interactions, motifs and network [PDF]

open access: yesCell Death & Disease, 2017
Yunyan Gu   +10 more
openaire   +2 more sources

Single‐Cell Analysis Reveals that Vitamin C Inhibits Bone Metastasis of Renal Cancer via Cell Cycle Arrest and Microenvironment Remodeling

open access: yesAdvanced Science, EarlyView.
3D‐cultured renal cancer cells exhibit stem‐like phenotypes and are more efficient in generating bone metastases. Vitamin C treatment can suppress the development of bone metastasis. Single‐cell transcriptomic analysis reveals that vitamin C inhibits metastasis by inducing tumor cell cycle arrest, suppressing osteoclast differentiation, and reducing ...
Jianye Zhang   +17 more
wiley   +1 more source

Contextual extracellular cues promote tumor cell EMT and metastasis by regulating miR-200 family expression [PDF]

open access: gold, 2009
Don L. Gibbons   +10 more
openalex   +1 more source

The E3 Ubiquitin Ligase ARIH1 Facilitates Colorectal Cancer Progression by Promoting Oxidative Phosphorylation via the Mitochondrial Translocation of K63‐Linked Ubiquitinated PHB1

open access: yesAdvanced Science, EarlyView.
The RBR E3 ubiquitin ligase ARIH1, which is upregulated in colorectal cancer cells, promotes cell growth and metastasis and correlates with an unfavorable CRC prognosis. Mechanistically, ARIH1 catalyzes K63‐linked ubiquitination of PHB1, enhancing the interaction between PHB1 and Akt.
Ying Tong   +13 more
wiley   +1 more source

The Interplay of SMAD4 and EMT in Oral Squamous Cell Carcinoma. [PDF]

open access: yesCancers (Basel)
Mozalbat S   +6 more
europepmc   +1 more source

Raf plus TGFβ-dependent EMT is initiated by endocytosis and lysosomal degradation of E-cadherin

open access: bronze, 2006
Elżbieta Janda   +5 more
openalex   +1 more source

EMT-Paramedic [PDF]

open access: bronze, 2009
Mark Allan LaGrave
openalex   +1 more source

MAGEA6 Engages a YY1‐Dependent Transcription to Dictate Perineural Invasion in Colorectal Cancer

open access: yesAdvanced Science, EarlyView.
This study investigates the role of MAGEA6 in perineural invasion (PNI) in colorectal cancer (CRC). MAGEA6 promotes CRC invasiveness by inhibiting YY1 ubiquitination, enhancing CXCL1 secretion, and recruiting Schwann cells. These findings highlight the potential of targeting the MAGEA6/YY1/CXCL1 axis for therapeutic strategies against PNI and tumor ...
Hao Wang   +9 more
wiley   +1 more source

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