Results 301 to 310 of about 366,025 (373)

The PI3K-AKT-mTOR signaling pathway mediates epithelial mesenchymal transition and cytoskeletal architecture changes induce to renal fibrosis after Bisphenol S exposure. [PDF]

Sci Rep
Zhang Z, Jin L, Mi T, Wang J, Wang Z, Luo J, Ren C, Wu X, Liu J, Guo P, Wang L, He D.   +11 more
europepmc   +1 more source

Figure S3 from <i>De novo</i> and histologically transformed small cell lung cancer is sensitive to lurbinectedin treatment through the modulation of EMT and NOTCH signaling pathways.

Subhamoy Chakraborty, Charles Coleman, Parvathy Manoj, Deniz Demircioğlu, Nisargbhai Shah, Elisa de Stanchina, Charles M. Rudin, Dan Hasson, Triparna Sen   +8 more
openalex   +1 more source

Genomic and Immune Correlates of EZH2 Expression and Activity in Olfactory Neuroblastoma

Head &Neck, EarlyView.
ABSTRACT Purpose Olfactory neuroblastoma (ONB) is a rare sinonasal malignancy with limited therapeutic options in the recurrent/metastatic setting; little is known regarding its responsiveness to immunotherapy. Inhibition of enhancer of zeste homolog 2 (EZH2) has been shown to improve T‐cell‐mediated killing and susceptibility to immune checkpoint ...
Elisabetta Xue, Tolulope Adeyelu, Harris Krause, Andrew Elliott, Ranee Mehra, Heloisa Soares, Emil Lou, Ari Vanderwalde, David Spetzler, Dara Bracken‐Clarke, Nyall R. London Jr., James L. Gulley, Charalampos S. Floudas   +12 more
wiley   +1 more source

The multifaceted role of E3 ubiquitin ligases in cancer metastasis: mechanisms, targets, and therapeutic implications. [PDF]

Essays Biochem
Singh M, Upreti A, Chattopadhyay S, Santra M.   +3 more
europepmc   +1 more source

Apigenin inhibits NF-κB and Snail signaling, EMT and metastasis in human hepatocellular carcinoma

, 2016
Yuan Qin, Dong Zhao, Honggang Zhou, Xinghui Wang, Weilong Zhong, Shuang Chen, Wenguang Gu, Wei Wang, Chunhong Zhang, Yanrong Liu, Huijuan Liu, Qiang Zhang, Yuanqiang Guo, Tao Sun, Cheng Yang   +14 more
openalex   +2 more sources

Waterpipe Smoke-Induced N6-Methyladenosine Modification Promotes the Progression of Oral Squamous Cell Carcinoma. [PDF]

Int Dent J
Prasad P, Jaber M, Khair AMB, Saeed MH, Ramasubramanian A, Arumugam P.   +5 more
europepmc   +1 more source

Th17 cells favor migration and invasiveness of cervical cancer cells under hypoxia in an IGF2BP2‐dependent manner

International Journal of Cancer, EarlyView.
What's New? Hypoxic regions and inflammatory Th17 cells in the tumor environment are both associated with poor prognosis in cervical cancer. However, synergistic mechanisms between hypoxia and Th17 cells remain elusive. This study demonstrated Th17–hypoxia‐driven mechanisms underlying cervical cancer progression.
Selina Gies, Maike Pohlers, Tanja Tänzer, Emmanuel Ampofo, Matthias W. Laschke, Moritz Schäfer, Yoo‐Jin Kim, Rainer Maria Bohle, Erich‐Franz Solomayer, Konrad Wagner, Martin Empting, Alexandra K. Kiemer, Barbara Walch‐Rückheim   +12 more
wiley   +1 more source

Copper modulates cell fate through the PLK1-FOXO3a-β-catenin signaling pathway by differentially regulating cuproptosis and EMT. [PDF]

Apoptosis
Lee HJ, Park JH, Kim DY, Kim DY, Yi MJ, Choi WS, Na HH, Chae S, Oh YT, Kim KC.   +9 more
europepmc   +1 more source

Endometrial Stromal Cell Senescence: A Non‐Negligible Factor in Recurrent Pregnancy Loss

iMetaMed, EarlyView.
As populations age, links between female reproductive aging and infertility are increasingly evident. Cellular senescence, characterized by near‐irreversible cell‐cycle arrest and accumulation of damage, can impair tissue function. In the endometrium, aberrant senescence of endometrial stromal cells (EnSCs) may compromise receptivity, hinder embryo ...
Shuang Wu, Cenlan Bu, Qinzheng Xu, Xi Cheng, Junrong Zhang, Jinling Chen, Yun‐Zhao Xu   +6 more
wiley   +1 more source

Stiffness-mediated paracrine signaling enhances induction of EMT in oral squamous cell carcinoma. [PDF]

APL Bioeng
Moon SY, Lamers ML, Engler AJ.
europepmc   +1 more source