Results 31 to 40 of about 23,157 (220)

Rational Development of Liposomal Hydrogels: A Strategy for Topical Vaginal Antiretroviral Drug Delivery in the Context of HIV Prevention

Pharmaceutics, 2019
HIV/AIDS stands as a global burden, and vaginal microbicides constitute a promising strategy for topical pre-exposure prophylaxis. Preceding the development of a microbicide containing tenofovir disoproxil fumarate (TDF) and emtricitabine (FTC), in ...
Maria J. Faria, Raul Machado, Artur Ribeiro, Hugo Gonçalves, Maria Elisabete C. D. Real Oliveira, Teresa Viseu, José das Neves, Marlene Lúcio   +7 more
doaj   +1 more source

Bioavailability of dissolved and crushed single tablets of bictegravir, emtricitabine, tenofovir alafenamide in healthy adults: the SOLUBIC randomized crossover study

Journal of Antimicrobial Chemotherapy, 2022
Background Crushing or dissolving bictegravir/tenofovir alafenamide/emtricitabine (BIC/TAF/FTC) tablets is not recommended because there are no data supporting this practice.
L. Hocqueloux, Sandrine Lefeuvre, J. Bois, S. Brucato, A. Alix, Cécile Valentin, L. Peyro-Saint-Paul, L. Got, F. Fournel, S. Dargère, T. Prazuck, A. Fournier, N. Grégoire, I. Mcnicholl, J. Parienti   +14 more
semanticscholar   +1 more source

Population pharmacokinetics of tenofovir, emtricitabine and intracellular metabolites in transgender women

British Journal of Clinical Pharmacology, 2022
Transgender women (TGW) have been underrepresented in trials and use gender‐affirming hormonal therapies (GAHT) that may alter renal function by significantly increasing creatinine clearance.
Asama Tanaudommongkon, A. Chaturvedula, C. Hendrix, E. Fuchs, Eugenie C. Shieh, R. Bakshi, M. Marzinke   +6 more
semanticscholar   +1 more source

A novel simultaneous high performance liquid chromatography-PDA method for the determination of Tenofovir AF, Darunavir, Emtricitabine and Cobicistat in bulk and its application to marketed formulation

Future Journal of Pharmaceutical Sciences, 2022
Background The present research article involves the simultaneous determination of Tenofovir alafenamide, Darunavir, Emtricitabine and Cobicistat in bulk as well as in tablet dosage form using high performance liquid chromatography. Result The separation
Challamalla Pavani, E. Susithra
doaj   +1 more source

Switching to Bictegravir, Emtricitabine, and Tenofovir Alafenamide in Virologically Suppressed Adults With Human Immunodeficiency Virus

Clinical Infectious Diseases, 2020
Background Bictegravir (B)/emtricitabine (F)/tenofovir alafenamide (TAF) is guideline-recommended treatment for human immunodeficiency virus type 1 (HIV-1).
P. Sax, J. Rockstroh, A. Luetkemeyer, Y. Yazdanpanah, D. Ward, B. Trottier, A. Rieger, Hui C. Liu, Rima K. Acosta, Sean E. Collins, D. Brainard, Hal Martin   +11 more
semanticscholar   +1 more source

The best backbone for HIV prevention treatment, and elimination: Emtricitabine+tenofovir

Antiviral Therapy, 2022
The advent of antiretroviral combination therapy has significantly impacted the HIV/AIDS epidemic. No longer a death sentence, HIV infection can be controlled and suppressed using cocktail therapies that contain two or more small molecule drugs.
R. Schinazi, Dharmeshkumar Patel, M. Ehteshami   +2 more
semanticscholar   +1 more source

Simultaneous determination of emtricitabine and tenofovir disoproxil fumarate in pharmaceutical preparations using spectrophotometric, chemometric and chromatographic methods [PDF]

Journal of the Serbian Chemical Society
Simple, accurate and sensitive spectrophotometric, chemometric and chromatographic methods were used for the simultaneous determination of emtricitabine (ETC) and tenofovir disoproxil fumarate (TDF) in tablets.
Dinçel Aysun, Gök-Topak Elif Damla, Onur Feyyaz   +2 more
doaj   +1 more source

Pre-exposure Prophylaxis Use by Breastfeeding HIV-Uninfected Women: A Prospective Short-Term Study of Antiretroviral Excretion in Breast Milk and Infant Absorption. [PDF]

PLoS Medicine, 2016
BACKGROUND:As pre-exposure prophylaxis (PrEP) becomes more widely used in heterosexual populations, an important consideration is its safety in infants who are breastfed by women taking PrEP.
Kenneth K Mugwanya, Craig W Hendrix, Nelly R Mugo, Mark Marzinke, Elly T Katabira, Kenneth Ngure, Nulu B Semiyaga, Grace John-Stewart, Timothy R Muwonge, Gabriel Muthuri, Andy Stergachis, Connie L Celum, Jared M Baeten   +12 more
doaj   +1 more source

Bictegravir, Emtricitabine & Tenofovir Alafenamide-associated Acute Pancreatitis

Translation, 2023
Please view the PDF to see the formatted meeting abstract.
Abdulmajeed Alharbi
doaj   +1 more source

Bictegravir/Emtricitabine/Tenofovir Alafenamide in Virologically Suppressed People with HIV Aged ≥ 65 Years: Week 48 Results of a Phase 3b, Open-Label Trial

Infectious Disease and Therapy, 2021
We report the 48-week results of an ongoing study to assess the efficacy and safety of switching older people with HIV to bictegravir/emtricitabine/tenofovir alafenamide (B/F/TAF).
F. Maggiolo, G. Rizzardini, J. Molina, F. Pulido, S. De Wit, L. Vandekerckhove, J. Berenguer, M. D’Antoni, C. Blair, S. Chuck, D. Piontkowsky, Hal Martin, R. Haubrich, I. Mcnicholl, J. Gallant   +14 more
semanticscholar   +1 more source