Results 81 to 90 of about 23,157 (220)

Sustained effect of Scotland's HIV pre‐exposure prophylaxis programme on transmission among gay and bisexual men who have sex with men: Population‐based retrospective cohort study

HIV Medicine, Volume 27, Issue 8, Page 1298-1311, August 2026.
Abstract Objectives To evaluate the population‐level impact of seven years of Scotland's HIV pre‐exposure prophylaxis (PrEP) programme among gay, bisexual and other men who have sex with men (GBMSM). Methods National administrative data were used to estimate PrEP coverage and HIV incidence among 35 342 GBMSM attending specialist sexual health services ...
Alan Yeung, Claudia Estcourt, Beth Cullen, Rebecca Metcalfe, Alison Rodger, Dan Clutterbuck, Nicola Steedman, Rak Nandwani, Duncan McCormick, Sharon Hutchinson   +9 more
wiley   +1 more source

Renal function in African women receiving tenofovir disoproxil fumarate as pre‐exposure prophylaxis for HIV during pregnancy and postpartum: A postpartum safety analysis in the CAP016 randomized control trial

HIV Medicine, Volume 27, Issue 8, Page 1333-1343, August 2026.
Abstract Background The effect of tenofovir disoproxil fumarate (TDF) when used as pre‐exposure prophylaxis (PrEP) on renal function in pregnant and postpartum women is understudied. An open‐label clinical trial (CAP016 study) was designed to examine the safety of TDF‐PrEP use during pregnancy and breastfeeding.
Gaysheen Kistan, Tonya Esterhuizen, Megeshinee Naidoo, Alicia C. Desmond, Motshedisi Sebitloane, Dhayendre Moodley   +5 more
wiley   +1 more source

Emtricitabine/Tenofovir Disoproxil Fumarate

Drugs, 2004
The nucleoside analogue reverse transcriptase inhibitor (RTI) emtricitabine and the nucleotide analogue RTI tenofovir disoproxil fumarate (tenofovir DF) have each shown antiviral activity against a number of HIV clinical isolates and cell lines. HIV variants with reduced susceptibility to emtricitabine and tenofovir have been selected for in vitro and ...
Toni M, Dando, Antona J, Wagstaff
openaire   +4 more sources

Acute Liver Toxicity due to Efavirenz/Emtricitabine/Tenofovir

Case Reports in Hepatology, 2015
The fixed-dose combination of Efavirenz/Emtricitabine/Tenofovir is a first-line agent for the treatment of HIV; however few cases have reported hepatotoxicity associated with the drug.
Rashmee Patil, Mel A. Ona, Haris Papafragkakis, Jeanne Carey, Yitzchak Moshenyat, Adib Alhaddad, Sury Anand   +6 more
doaj   +1 more source

Unintended Consequences of Life‐Saving Pharmaceutical Innovations: How HAART Led to the Resurgence of Syphilis

Health Economics, Volume 35, Issue 7, Page 1118-1130, July 2026.
ABSTRACT Syphilis, a sexually transmitted infection that can lead to serious health complications, was almost eliminated in the United States by 2000. But since then, its incidence began to increase, recently reaching a 60‐year peak. We suggest that the introduction of the highly active antiretroviral therapy (HAART) drug regimen, which transformed HIV
David Beheshti, Scott Cunningham, Nir Eilam   +2 more
wiley   +1 more source

Design and validation of a robust RP-UPLC approach for simultaneous quantification of emtricitabine, tenofovir, and nelfinavir in active pharmaceutical ingredients and finished dosage products

Journal of Applied Pharmaceutical Research
Background: Fixed-dose combinations of antiretroviral agents such as Emtricitabine (EMT), Tenofovir (TEN), and Nelfinavir (NEL) are central to Human Immunodeficiency Virus (HIV) therapy.
Gayathri N, Kannappan N, Srinivasan N, Surendra Kumar M   +3 more
doaj   +1 more source

The Role of Implicit Bias in Shaping Medication Prescribing Practices: A Scoping Review

JACCP: JOURNAL OF THE AMERICAN COLLEGE OF CLINICAL PHARMACY, Volume 9, Issue 7, July 2026.
ABSTRACT Background The most significant risk of implicit bias is that it is often unrecognized and unaddressed. Unidentified implicit bias in health care can hinder the appropriate prescribing of medications in underserved groups. This requires the strategic measurement of implicit bias to assess its impact, using methods such as the implicit ...
Angel M. Edwards, Olubukola A. Tikare, Noelia Dulo, Antoinette B. Coe, Steven R. Erickson, Michael P. Dorsch   +5 more
wiley   +1 more source

Doravirine/Lamivudine/Tenofovir Disoproxil Fumarate is Non-inferior to Efavirenz/Emtricitabine/Tenofovir Disoproxil Fumarate in Treatment-naive Adults With Human Immunodeficiency Virus–1 Infection: Week 48 Results of the DRIVE-AHEAD Trial

Clinical Infectious Diseases, 2018
In Human Immunodeficiency Virus–1 treatment-naive adults, a fixed combination of doravirine/lamivudine/tenofovir disoproxil fumarate demonstrated non-inferior antiretroviral efficacy to efavirenz/emtricitabine/tenofovir disoproxil fumarate at week 48 ...
C. Orkin, K. Squires, J. Molina, P. Sax, W. Wong, O. Sussmann, R. Kaplan, L. Lupinacci, A. Rodgers, Xia Xu, G. Lin, Sushma Kumar, P. Sklar, B. Nguyen, G. Hanna, C. Hwang, E. Martin   +16 more
semanticscholar   +1 more source

Antiviral Efficacies of FDA-Approved Drugs against SARS-CoV-2 Infection in Ferrets

mBio, 2020
Due to the urgent need of a therapeutic treatment for coronavirus (CoV) disease 2019 (COVID-19) patients, a number of FDA-approved/repurposed drugs have been suggested as antiviral candidates at clinics, without sufficient information. Furthermore, there
Su-Jin Park, Kwang-Min Yu, Young-Il Kim, Se-Mi Kim, Eun-Ha Kim, Seong-Gyu Kim, Eun Ji Kim, Mark Anthony B. Casel, Rare Rollon, Seung-Gyu Jang, Min-Hyeok Lee, Jae-Hyung Chang, Min-Suk Song, Hye Won Jeong, Younho Choi, Weiqiang Chen, Woo-Jin Shin, Jae U. Jung, Young Ki Choi   +18 more
doaj   +1 more source

Intracellular Tenofovir-Diphosphate and Emtricitabine-Triphosphate in Dried Blood Spots Following Tenofovir Alafenamide: The TAF-DBS Study.

Journal of Acquired Immune Deficiency Syndromes, 2020
BACKGROUND Tenofovir alafenamide (TAF), in combination with FTC, was recently approved for PrEP in the United States. The objective of this study was to assess the relationship between tenofovir-diphosphate (TFV-DP) and emtricitabine-triphosphate (FTC-TP)
J. Yager, J. Castillo-Mancilla, Mustafa E. Ibrahim, Kristina M. Brooks, C. Mchugh, Mary Morrow, S. McCallister, Lane R. Bushman, S. MaWhinney, J. Kiser, P. Anderson   +10 more
semanticscholar   +1 more source