Rhodium/phospholane-phosphite catalysts give unusually high regioselectivity in the enantioselective hydroformylation of vinyl arenes [PDF]
, 2014 Using the phospholane-phosphite ligand, BOBPHOS, almost perfect regioselectivities and high enantioselectivities (up to 92% ee) are observed in Rh catalysed enantioselective hydroformylation of vinyl arenes.
Clarke, Matthew L. +3 more
core +1 more source
Critical Assessment of the Anti-Inflammatory Potential of Usnic Acid and Its Derivatives—A Review
Life, 2023 Inflammation is a response of the organism to an external factor that disrupts its natural homeostasis, and it helps to eliminate the cause of tissue injury.
Wojciech Paździora +5 more
doaj +1 more source
Enantioselective Organocatalytic Diels-Alder Trapping of Photochemically Generated Hydroxy-o-Quinodimethanes [PDF]
, 2016 The photoenolization/Diels-Alder strategy offers straightforward access to synthetically valuable benzannulated carbocyclic products. This historical light-triggered process has never before succumbed to efforts to develop an enantioselective catalytic ...
Cuadros, Sara +3 more
core +2 more sources
Enantioselective synthesis of (−)-paeonilide [PDF]
Chemical Communications, 2012 The first enantioselective synthesis of (−)-paeonilide is reported. Starting from inexpensive furan-3-carboxylic acid the targeted monoterpene was obtained in 12 steps via an asymmetric cyclopropanation-lactonization cascade and a stereoselective side chain insertion at an acetal-like position.
Harrar, Klaus, Reiser, Oliver
openaire +3 more sources
Enantioselective Desymmetrization of FTY720
Chemical and Pharmaceutical Bulletin, 2014 A method for enantioselective desymmetrization of N-Ac and N-Boc-FTY720 by nonenzymatic asymmetric acylation was developed. Effective enantioselective monobenzoylation using benzoyl chloride in the presence of the tetraphenylbisoxazoline (L2)-CuCl2 complex gave the desired products 3a and 3b in 52-62% yield with 64% ee.
Hidemasa, Hikawa +5 more
openaire +3 more sources
Enantioselective Hydrocarbamoylation of Alkenes
Angewandte Chemie International Edition, 2022 AbstractThe asymmetric hydroaminocarbonylation of olefins represents a straightforward approach for the synthesis of enantioenriched amides, but is hampered by the necessity to employ CO gas, often at elevated pressures. We herein describe, as an alternative, an enantioselective hydrocarbamoylation of alkenes leveraging dual copper hydride and ...
Sheng Feng +2 more
openaire +2 more sources
Enantioselective Synthesis of (−)-Acetylapoaranotin
Organic Letters, 2017 The first enantioselective total synthesis of the epipolythiodiketopiperazine (ETP) natural product (-)-acetylapoaranotin (3) is reported. The concise synthesis was enabled by an eight-step synthesis of a key cyclohexadienol-containing amino ester building block.
Haoxuan Wang +5 more
openaire +3 more sources
Cascade radical reaction of substrates with a carbon–carbon triple bond as a radical acceptor
Beilstein Journal of Organic Chemistry, 2013 The limitation of hydroxamate ester as a chiral Lewis acid coordination moiety was first shown in an intermolecular reaction involving a radical addition and sequential allylation processes.
Hideto Miyabe +2 more
doaj +1 more source
Synthesis of Solution-Phase Phosphoramidite and Phosphite Ligand Libraries and Their In Situ Screening in the Rhodium-Catalyzed Asymmetric Addition of Arylboronic Acids [PDF]
, 2007 Herein, we report the automated parallel synthesis of solution-phase libraries of phosphoramidite ligands for the development of enantioselective catalysts.
Feringa, Ben L., +5 more
core +1 more source
Molecules, 2010 Enantiomerically enriched hydroxy-substituted b-amino esters have been synthesized through CAL-B-catalyzed enantioselective hydrolysis in organic media.
Enikő Forró +5 more
doaj +1 more source