Results 31 to 40 of about 19,171 (285)
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Active networks: an evolution of the internet [PDF]
, 2001 Active Networks can be seen as an evolution of the classical model of packet-switched networks. The traditional and ”passive” network model is based on a static definition of the network node behaviour. Active Networks propose an “active” model where the
Di Fatta, Giuseppe, Lo Re, Giuseppe
core
A Framework for Rapid Development and Portable Execution of Packet-Handling Applications [PDF]
, 2005 This paper presents a framework that enables the execution of packet-handling applications (such as sniffers, firewalls, intrusion detectors, etc.) on different hardware platforms.
Baldi, Mario +1 more
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Global state, local decisions: Decentralized NFV for ISPs via enhanced SDN [PDF]
, 2017 The network functions virtualization paradigm is rapidly gaining interest among Internet service providers. However, the transition to this paradigm on ISP networks comes with a unique set of challenges: legacy equipment already in place, heterogeneous ...
Barkai, Sharon +7 more
core +2 more sources
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
FEBS Open Bio, EarlyView.Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
Biodegradable polymer network encapsulated polyplex for DNA delivery
RSC Advances, 2013 A novel gene delivery system is made by encapsulation of a polyplex between pDNA and cationic micelles with a biodegradable crosslinked shell. The outer shell can provide additional functionality to the system and protect DNA from degradation. The encapsulated polyplex exhibits a similar transfection efficiency compared to the naked polyplex.
Petar D. Petrov +3 more
openaire +1 more source
Fast emergency paths schema to overcome transient link failures in ospf routing
, 2012 A reliable network infrastructure must be able to sustain traffic flows, even when a failure occurs and changes the network topology. During the occurrence of a failure, routing protocols, like OSPF, take from hundreds of milliseconds to various seconds ...
Barreto, Fernando +2 more
core +1 more source
Field-based branch prediction for packet processing engines [PDF]
, 2009 Network processors have exploited many aspects of architecture design, such as employing multi-core, multi-threading and hardware accelerator, to support both the ever-increasing line rates and the higher complexity of network applications.
Bermingham, David +3 more
core +1 more source
FEBS Open Bio, EarlyView.Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source