Age-related increase in plasma p-tau217 in amyloid-beta-negative cognitively unimpaired individuals affects diagnostic interpretation. [PDF]
Alzheimers DementAbstract INTRODUCTION The extent to which non‐pathological aging influences plasma biomarkers remains unclear. Here, we investigate factors influencing plasma p‐tau217 levels in cognitively unimpaired (CU), amyloid‐beta–negative (Aβ‐) individuals. METHODS Plasma p‐tau217 was measured in CU Aβ‐ positron emission tomography–negative (PET‐) participants ...
Mammel AE +11 more
europepmc +2 more sources
Radiometric Constraints on the Timing, Tempo, and Effects of Large Igneous Province Emplacement
Geophysical Monograph Series, Page 27-82., 2021 Exploring the links between Large Igneous Provinces and dramatic environmental impact
An emerging consensus suggests that Large Igneous Provinces (LIPs) and Silicic LIPs (SLIPs) are a significant driver of dramatic global environmental and biological changes, including mass extinctions.
Jennifer Kasbohm +2 more
wiley +1 more source
Critical role of keratinocytes and protease-activated receptor 2 in secondary lymphedema development. [PDF]
Clin Transl MedActivated keratinocytes play an important role in the early stage of the pathophysiology of secondary lymphedema through PAR2 signaling. Lymphatic injury‐induced protease activation stimulates keratinocyte PAR2 signaling, driving hyperkeratosis and Th2 inflammation, which can be therapeutically attenuated by teriflunomide. Abstract Background Secondary
Park HJ +18 more
europepmc +2 more sources
Masculinidad hegemónica. Repensando el concepto
Revista del laboratorio iberoamericano para el estudio sociohistórico de las sexualidades, 2021 El concepto de masculinidad hegemónica ha influenciado los estudios de género en varios campos académicos, pero también ha generado serias críticas. Les autores rastrean el origen del concepto en una convergencia de ideas de principios de la década de ...
R.W, Connell +3 more
doaj +1 more source
Cambios postpandemia covid-19 en Micro, Pequeñas y Medianas Empresas (MIPYMES) de Encarnación
Innovación EmpresarialObjetivo. Identificar los cambios en la gestión empresarial de las mipymes de la ciudad de Encarnación, Paraguay, en el periodo posterior a la pandemia de la covid-19. Métodos.
Marcelino Venialgo Figueredo +3 more
doaj +1 more source
El estado del arte en la Comunicación Estratégica
Mediaciones Sociales, 2012 Todo indica que el problema de bosquejar el estado del arte de la comunicación es-tratégica no es tanto concretar el estado de la cuestión (dónde estamos) cuanto concre-tar la cuestión cuyo estado se pretende precisar (de qué fenómeno estamos hablan-do).
Rafael Alberto Pérez
doaj +1 more source
Michel Henry e os problemas da encarnação: o corpo doente
Psicologia USP, 2015 Resumo: Em sua teoria da encarnação, Michel Henry subverte radicalmente o paradigma cartesiano tal como é entendido pela fenomenologia tradicional, oferecendo à psicologia e a outras áreas do saber a concepção da indissociabilidade entre a subjetividade ...
Maristela Vendramel Ferreira
doaj +1 more source
Water, Sanitation and Health: The World Bank's Financing of Sustainable Development Goal 6
Sustainable Development, EarlyView.ABSTRACT The World Bank has an explicit commitment to financing projects aimed at ensuring access to drinking water and sanitation (SDG 6), given their implications for countries' development. The objective of this study is to analyse its performance over the past decades, in order to understand the evolution of the allocated amount and the ...
Cristina Martínez‐Gómez +2 more
wiley +1 more source
HeritageHumanity is opening up to cosmos in all its dimensions and areas of knowledge. In this context, Paraguay, due to its multicultural uniqueness and two official languages (Spanish and Guaraní), represents an emblematic example of how legends, traditions ...
Jesús Martínez-Frías +5 more
doaj +1 more source
The Modern Law Review, EarlyView.Exemplary damages are commonly understood as public interest awards. This article explores the logical implications of understanding them in this way for a tort claimant's rights of action and settlement, and for the proper distribution of awards. One implication, it suggests, is that settlements, being compromises of public ends, should require court ...
Kit Barker
wiley +1 more source