Results 81 to 90 of about 38,408 (221)

Impaired intrinsic immunity to HSV-1 in human iPSC-derived TLR3-deficient CNS cells [PDF]

, 2012
In the course of primary infection with herpes simplex virus 1 (HSV-1), children with inborn errors of TLR3 immunity are prone to HSV-1 encephalitis (HSE) 1–3.
Abel, Laurent, Abhyankar, Avinash, Al-Muhsen, Saleh, Casanova, Jean-Laurent, Ciancanelli, Michael J., Daley, George Quentin, Elkabetz, Yechiel, Goldstein, Peter A., Herman, Melina, Jouanguy, Emmanuelle, Keros, Sotirios, Lafaille, Fabien G, Mostoslavsky, Gustavo, Notarangelo, Luigi D., Ordovas-Montanes, Jose Manuel, Pessach, Itai M., Plancoulaine, Sabine, Schlaeger, Thorsten M., Studer, Lorenz, Tardieu, Marc, Tu, Edmund, Ying, Shui-Wang, Zhang, Shen-Ying   +22 more
core   +1 more source

Eczema Monkeypoxicum Following Sexual Transmission Treated With Tecovirimat

JEADV Clinical Practice, Volume 5, Issue 1, Page 250-253, March 2026.
Capsule summary Mpox is a zoonotic infection that may present severe dissemination in patients with pre‐existing dermatoses. We report a 30‐year‐old man with active atopic dermatitis who developed extensive, sexually transmitted mpox with widespread cutaneous involvement consistent with eczema monkeypoxicum.
Andrés Vidal González, Sergio López Alcázar, José Ángel Amat Sánchez, Francisco Vergara Barria, Rosa Feltes Ochoa, Elena Sendagorta Cudos, Pedro Herranz Pinto   +6 more
wiley   +1 more source

Varicella Zoster Virus Infection: Clinical Features, Molecular Pathogenesis, Treatment, and Prevention

MedComm, Volume 7, Issue 3, March 2026.
This review focuses on the clinical features, molecular mechanisms, treatment methods, and preventive measures of the VZV, with the aim of providing a theoretical basis for the development of new treatment and prevention methods for HZ. ABSTRACT Varicella zoster virus (VZV) is a ubiquitous human herpesvirus that establishes lifelong latency and causes ...
Lei Peng, Honghao Song, Tianying Li, Yuqing Ma, Chen Yan, Yuhan Cao, Kaiqiang Sun, Chaofeng Han, Hongbin Yuan   +8 more
wiley   +1 more source

Antiherpes simplex virus type 2 activity of the antimicrobial peptide subtilosin [PDF]

, 2014
In the present study we evaluated the antiviral activity of subtilosin, a cyclical peptide isolated from Bacillus amyloliquefaciens, against herpes simplex virus type 2 (HSV-2) in cell cultures and we investigated subtilosin mode of action. We determined,
Castilla, Viviana, Chikindas, Michael, Quintana, Verónica Mara, Sinko, Patrick J., Torres, Nicolás, Wachsman, Mónica B.   +5 more
core   +1 more source

Human Cyclophilins—An Emerging Class of Drug Targets

Medicinal Research Reviews, Volume 46, Issue 2, Page 475-512, March 2026.
ABSTRACT Cyclophilins are a family of enzymes with peptidyl‐prolyl isomerase activity found in all cells of all organisms. To date, 17 cyclophilin isoforms have been identified in the human body, participating in diverse biological processes. Consequently, cyclophilins have emerged as promising targets for drug development to address a wide array of ...
Katarina Jurkova, Hana Navratilova, Kamil Musilek, Ondrej Benek   +3 more
wiley   +1 more source

'Unforgettable' : a pictorial essay on anatomy and pathology of the hippocampus [PDF]

, 2017
The hippocampus is a small but complex anatomical structure that plays an important role in spatial and episodic memory. The hippocampus can be affected by a wide range of congenital variants and degenerative, inflammatory, vascular, tumoral and toxic ...
Achten, Eric, Acou, Marjan, DE GROOTE, JEROEN, De Kock, Isabelle, Deblaere, Karel, Dekeyzer, Sven, Nikoubashman, Omid, VAN EETVELDE, RUTH, Vanden Bossche, Stephanie, Wiesmann, Martin   +9 more
core   +2 more sources

Novel applications of the tomato microbiome: Roles and considerations for agriculture, human health, and society

PLANTS, PEOPLE, PLANET, Volume 8, Issue 2, Page 530-555, March 2026.
Plants, like humans, have a microbiome that helps them grow, defend themselves against pathogens, acquire nutrients, and protect themselves against environmental stresses. The microbiome of tomatoes, a staple crop grown worldwide, could be utilized not only to reduce fertilizer and pesticide applications, but also to clean up harmful pollutants ...
Sean Lindert, Kathryn Kingsley, Peerapol Chiaranunt, James F. White   +3 more
wiley   +1 more source

A case of atypical disseminated herpes simplex virus 1 with hepatitis in a liver transplant recipient: the need for dermatologic evaluation [PDF]

, 2020
Disseminated herpes simplex virus (HSV) is mainly seen in immunocompromised individuals. Atypical lesions can be present in both primary infection and reactivation disease. Compared with the general population, inmunocompromised hosts are at greater risk
Bea-Ardebol, S, Burgos-Blasco, Patricia, Fernandez-Nieto, D, Jimenez-Cauhe, J, Ortega-Quijano, D, Pindado-Ortega, Cristina   +5 more
core  

Tick-borne encephalitis virus induces chemokine RANTES expression via activation of IRF-3 pathway. [PDF]

, 2016
BACKGROUND: Tick-borne encephalitis virus (TBEV) is one of the most important flaviviruses that targets the central nervous system (CNS) and causes encephalitides in humans. Although neuroinflammatory mechanisms may contribute to brain tissue destruction,
Bai, B, Cui, Z, Hu, Q, Liu, X, Luo, M, Ma, X, Mao, P, Shu, B, Wang, H, Zhang, X, Zheng, Z   +10 more
core   +3 more sources

Proteomic Analysis of Cerebrospinal Fluid from Severe COVID‐19 Patients Reveals Prognostic Biomarkers Associated with Disease Outcome

PROTEOMICS – Clinical Applications, Volume 20, Issue 2, March 2026.
ABSTRACT Purpose Coronavirus disease 2019 (COVID‐19) has highlighted significant neurological complications in severe cases. Cerebrospinal fluid (CSF) proteomics could reveal biomarkers related to clinical outcome among critically ill patients. Experimental Design We performed high‐resolution proteomic analyses of CSF samples from 29 intensive care ...
Harry Alexopoulos, Martina Samiotaki, Eirini Gkogkou, Sofia Mavromati, Kleopatra Bitzogli, Georgios Panagiotou, Athanasios Tzioufas, Eleni Magira, Αnastasia Kotanidou, Ioannis Trougakos   +9 more
wiley   +1 more source