Results 121 to 130 of about 1,546,162 (239)
Vaccination remains the sole effective strategy for combating Japanese encephalitis (JE). Both inactivated and live attenuated vaccines exhibit robust immunogenicity. However, the production of these conventional vaccine modalities necessitates extensive
Takele Adugna +14 more
doaj +1 more source
Androlaelaps fahrenhoizi, a potential vector of zoonotic diseases, is widely distributed in southwest China, predominantly infesting A. agrarius mice. The mite infestation is aggregated, and has environmental heterogeneity and age bias of hosts. Abundant A.
Xue‐Jiao Zhu +3 more
wiley +1 more source
Treatment options for immune‐related adverse events associated with immune checkpoint inhibitors
Abstract The immunotherapy revolution with the use of immune checkpoint inhibitors (ICIs) started with the clinical use of the first ICI, ipilimumab, in 2011. Since then, the field of ICI therapy has rapidly expanded — with the FDA approval of 10 different ICI drugs so far and their incorporation into the therapeutic regimens of a range of malignancies.
Yu Hua Chen +3 more
wiley +1 more source
A Transcriptomic Analysis of Cancer‐Stromal Interactome in Lung Cancer Xenograft Models
We conducted a comprehensive analysis of the lung cancer interactome to identify key ligand–receptor pairs involved in the aggressiveness of lung adenocarcinoma. Tumor necrosis factor superfamily member 12 and its receptor tumor necrosis factor receptor superfamily member 12A signaling axis may be potential candidates for therapeutic intervention for ...
Yuriko Takayama‐Isagawa +16 more
wiley +1 more source
The global Phase 3 IMpower010 study (NCT02486718) evaluated atezolizumab versus best supportive care (BSC) after complete resection and adjuvant platinum‐based chemotherapy in patients with stage IB–IIIA non‐small cell lung cancer (NSCLC). Here, we report updated efficacy and safety results from the disease‐free survival (DFS) final and overall ...
Morihito Okada +9 more
wiley +1 more source
Outbreak of West Nile Virus Infection in Kerala
West Nile virus infection may present as encephalitis and is transmitted through the bite of an infected mosquito.
P S Shankar
doaj +1 more source
Summary Borna disease is an acute to subacute, rarely chronic non‐purulent meningoencephaylomyelitis affecting mainly horses and sheep. This case series describes the clinical signs, diagnosis, treatment, outcome and post‐mortem findings of five horses and two donkeys with this condition. The equids affected were geldings or mares of various breeds and
I. L. Piotrowski, M. Hilbe, H. K. Junge
wiley +1 more source
Sex Differences in Response to Viral Vector Vaccines—Implications for Future Vaccine Design
ABSTRACT Vaccination represents one of the most impactful public health achievements, preventing 3.5 to 5 million deaths annually according to estimates of the World Health Organization. Yet, recent outbreaks of emerging and reemerging infectious diseases highlight the need for rapid and strategic vaccine development using vaccine platforms ...
Ilka Grewe +2 more
wiley +1 more source
Japanese encephalitis: a review of the Indian perspective
Japanese encephalitis virus (JEV) causes Japanese encephalitis, which is a leading form of viral encephalitis in Asia, with around 50,000 cases and 10,000 deaths per year in children below 15 years of age.
Sarika Tiwari +3 more
doaj +1 more source
Sex Differences in Metabolite–Immune Circuits of Neuroinflammation
ABSTRACT Sex is a fundamental yet underexplored determinant of human neuroinflammation. Across autoimmune, neurodegenerative, and post‐infectious neurological syndromes, males and females exhibit consistent differences in disease vulnerability, progression, and immune tone.
Priyanka Saminathan +6 more
wiley +1 more source

