Results 21 to 30 of about 27,055 (184)

Japanese Encephalitis Virus in Meningitis Patients, Japan

Emerging Infectious Diseases, 2005
Cerebrospinal fluid specimens from 57 patients diagnosed with meningitis were tested for Japanese encephalitis virus. Total RNA was extracted from the specimens and amplified.
Masaru Kuwayama, Mikako Ito, Shinichi Takao, Yukie Shimazu, Shinji Fukuda, Kazuo Miyazaki, Ichiro Kurane, Tomohiko Takasaki   +7 more
doaj   +1 more source

Clinical profile and outcome of acute encephalitis syndrome (AES) patients treated in College of Medical Sciences-Teaching Hospital

Journal of College of Medical Sciences-Nepal, 2014
Objective: Acute encephalitis syndrome is a cause of significant morbidity and mortality in Nepal. Although Japanese encephalitis virus (JEV) was thought to be a major cause for acute encephalitis syndrome, more non-Japanese encephalitis virus cases
Lekhjung J Thapa, RS Twayana, R Shilpakar, MR Ghimire, A Shrestha, S Sapkota, PVS Rana   +6 more
doaj   +1 more source

Changing Paradigm in the epidemiology of Japanese encephalitis in India

Journal of Vector Borne Diseases, 2022
Japanese encephalitis (JE) is a very serious public health problem in India and the conducive environment permit its emergence in non-endemic areas in the country.
Philip Samuel Paulraj, Veeramanoharan Rajamannar, Govindarajan Renu, Ashwani Kumar   +3 more
doaj   +1 more source

Japanese Encephalitis Complicated with Obstructive Hydrocephalus [PDF]

Journal of Clinical and Diagnostic Research, 2016
Japanese Encephalitis (JE), caused by Japanese encephalitis virus (JEV), a flavi-virus, is the most significant aetiology of arboviral encephalitis worldwide. It has resulted in epidemics of encephalitis in the Indian subcontinent.
Vivek Suman, Ujjawal Roy, Ajay Panwar, Alpana Raizada   +3 more
doaj   +1 more source

A Prospective Study of Individuals at Risk of Multiple Sclerosis Informs the Design of Primary Prevention Studies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen, Ceren Tozlu, Tina Roostaei, Fatoumata Diallo, Kaho Onomichi, Jiyeon Son, Zongqi Xia, Philip L. De Jager   +7 more
wiley   +1 more source

Minocycline for management of Japanese encephalitis: A case report

Journal of Vector Borne Diseases
Japanese encephalitis virus infection manifests as acute encephalitis syndrome leading to significant neurological disability with estimated incidence around 85,000 cases per year and case fatality rate of 30%.
Naveenraj Palaniswamy, PM Azarudheen, Syam Unnikrishnan   +2 more
doaj   +1 more source

RNF138‐Mediated Ubiquitination and Degradation of NS5 Restricts Tick‐Borne Encephalitis Virus Infection

Advanced Science, EarlyView.
Host‐specific compatibility between RNF138‐like proteins and flavivirus NS5 determines NS5 stability. Mammalian RNF138 but not arthropod homologs recognizes and induces conserved NS5/RdRp K48‐linked ubiquitination and proteasomal degradation, thereby restricting viral replication. Ectopic RNF138 in mice attenuates TBEV‐induced pathogenesis. (Created in
Jialiang Sun, Weijing Yang, Hao Zhou, Shuai Li, Xin Jiang, Jianyang Gu, Wenyan Zhang   +6 more
wiley   +1 more source

Japanese encephalitis virus: An overview

Journal of Vector Borne Diseases
Japanese encephalitis (JE) is a mosquito-borne infectious disease caused by the Japanese encephalitis virus (JEV), posing a substantial threat to human health and property and safety.
Qiuyang Li, Xiaoling Cheng, Min Luo, Jinrong Shi   +3 more
doaj   +1 more source

Mixed Upper and Lower Motor Neuron Damage in Japanese Encephalitis Virus Infection

Case Reports in Neurology, 2020
Cerebral manifestations in Japanese B encephalitis are well known. However, there are very few studies focusing on extra-cerebral manifestations, among which focal anterior horn cell involvement is exceedingly rare.
Ritwik Ghosh, Souvik Dubey, Subhankar Chatterjee, Biman Kanti Ray, Julián Benito-León   +4 more
doaj   +1 more source

ZNF33B Promotes Japanese Encephalitis Virus Infection by Regulating the Stability of M6A‐Modified Trim25 to Control the Autophagy Process

Advanced Science, EarlyView.
Upon JEV infection, ZNF33B recruits METTL14 to stabilize the METTL3‐METTL14 m6A methyltransferase complex, leading to increased m6A modification of host transcripts, including Trim25 mRNA. ZNF33B selectively binds m6A‐modified sites on Trim25 mRNA and accelerates its decay, resulting in reduced TRIM25 protein abundance.
Jian Du, Chunwei Li, Jiyuan Luo, Huizhi Zhang, Jinyan Zhang, Suya Wang, Huanchun Chen, Hongli Xu, Xiangmin Li, Ping Qian   +9 more
wiley   +1 more source