Results 101 to 110 of about 176,364 (292)
Advanced Genetics, Volume 6, Issue 2, June 2025.This review provides a detailed description of gene mutations and epigenetic mechanisms in central nervous system (CNS) disease, strategies for gene therapy, challenges for CNS gene therapy and gene‐drug nanocarriers. This review also summarizes the applications of nanogenetic therapy platforms in CNS diseases (brain tumors, neurodegenerative diseases,
Fuming Liang +4 more
wiley +1 more source
Glia, EarlyView.ABSTRACT Multiple sclerosis (MS) is the most common non‐infectious inflammatory CNS disease, characterized by progressive neurodegeneration and focal demyelinated lesions. Traditionally considered an autoimmune disease, MS is driven by the immune system's attack on CNS myelin, resulting in cumulative disability.
Volker Siffrin
wiley +1 more source
Uncoupling in a child with tonic seizures
Epileptic Disorders, EarlyView.
Émilie Groulx‐Boivin +1 more
wiley +1 more source
Diverse Subpopulations of Reactive Astrocytes Following Chronic Toxoplasma Infection
Glia, EarlyView.Toxoplasma infection results in distinct astrocyte subpopulations. Chronically labeled reactive astrocytes appear transcriptionally plastic and can regain acute inflammatory responding and naive homeostatic astrocytic gene patterns in the presence of ongoing neuroinflammation.
Zoe A. Figueroa +7 more
wiley +1 more source
Ibrain, Volume 11, Issue 1, Page 98-105, Spring 2025.Mendelian randomization (MR) studies were conducted using the inverse‐variance weighted (IVW) method, MR‐Egger and weighted median on juvenile myoclonic epilepsy (JME), and systemic lupus erythematosus (SLE) data from the Integrative Epidemiology Unit (IEU) Open genome‐wide association study (GWAS) database and the International League Against Epilepsy
Sirui Chen +10 more
wiley +1 more source
International Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 23-30, April 2025.Abstract Autoimmune encephalitis is a group of disorders characterized by symptoms of dysfunction of the limbic and extra‐limbic systems that occur in association with antibodies against intracellular antigens, synapses, or proteins located on the surface of nerve cells. Anti‐NMDA (N‐methyl‐D‐aspartate) receptor encephalitis was first described in 2007
Pham Ba Nha +6 more
wiley +1 more source
Journal of General and Family Medicine, EarlyView.This case report describes a 24‐year‐old woman with trisomy 21 and an incomplete childhood vaccination history who developed severe disseminated varicella and varicella pneumonia. Chest CT on admission day 3 revealed scattered small nodules in both lung fields, characteristic of varicella pneumonia.
Satoshi Inaba +3 more
wiley +1 more source