Diffusion Tractography Biomarker for Epilepsy Severity in Children With Drug‐Resistant Epilepsy
ABSTRACT Objective To develop a novel deep‐learning model of clinical DWI tractography that can accurately predict the general assessment of epilepsy severity (GASE) in pediatric drug‐resistant epilepsy (DRE) and test if it can screen diverse neurocognitive impairments identified through neuropsychological assessments.
Jeong‐Won Jeong +7 more
wiley +1 more source
A narrative review of antiseizure medication adherence in epilepsy: determinants to clinical implications [PDF]
Achieving optimal seizure control without recurrence is a critical goal in epilepsy. When evaluating whether treatment is effective, medication adherence must be carefully considered but has traditionally been overlooked.
Yongmoo Kim, Yoonhyuk Jang
doaj +1 more source
Pitfalls associated with the use of molecular diagnostic panels in the diagnosis of cryptococcal meningitis [PDF]
We report the case of a kidney transplantation patient on chronic immunosuppressive therapy presenting with subacute meningitis. The final diagnosis of cryptococcal meningitis was delayed due to 2 false-negative cryptococcal results on a molecular ...
Burnham, Carey-Ann +5 more
core +2 more sources
Neurological manifestations and neuro-invasive mechanisms of the severe acute respiratory syndrome coronavirus type 2 [PDF]
Background and purpose Infections with coronaviruses are not always confined to the respiratory tract and various neurological manifestations have been reported.
Boon, Paul +6 more
core +2 more sources
Clinical Characteristics and Outcomes of Early‐Onset Versus Late‐Onset LGI1‐Antibody Encephalitis
ABSTRACT Background Leucine‐rich glioma‐inactivated 1 antibody (LGI1‐Ab) encephalitis predominantly affected older individuals, but has also been reported in younger patients. However, the demographic, clinical, and prognostic characteristics of early‐onset LGI1‐Ab encephalitis have yet to be systematically elucidated. This study aims to systematically
Yu Kong +7 more
wiley +1 more source
Abstract Autoimmune encephalitis (AE) is an increasingly recognized, potentially life-threatening disorder that poses a diagnostic challenge in the intensive care setting because of its variable clinical presentation. Various epidemiologic studies show that AE has incidence and prevalence rates similar to those of infectious encephalitis.
Eslam Shosha, Sean J. Pittock
openaire +3 more sources
PREVALENCE OF HEPATITIS E MARKERS IN CHILDREN
Aim. Frequency of detection determination for past and current hepatitis E virus (HEV) infection markers in children with immune suppression, as well as children with normal immune status. Materials and methods.
I. A Potemkin +11 more
doaj
Predictors of poor outcomes in neuroleptospirosis and differentiation from tuberculous meningitis: a cross-sectional analysis [PDF]
Purpose This study was performed to identify predictors of poor outcomes in neuroleptospirosis and delineate key clinical, laboratory, and imaging parameters that differentiate it from tuberculous meningitis (TBM).
Abhishek Dixit
doaj +1 more source
Insights Into the Antigenic Repertoire of Unclassified Synaptic Antibodies
ABSTRACT Objective We sought to characterize the sixth most common finding in our neuroimmunological laboratory practice (tissue assay‐observed unclassified neural antibodies [UNAs]), combining protein microarray and phage immunoprecipitation sequencing (PhIP‐Seq). Methods Patient specimens (258; 133 serums; 125 CSF) meeting UNA criteria were profiled;
Michael Gilligan +22 more
wiley +1 more source
Analysis of tick-borne encephalitis virus-induced host responses in human cells of neuronal origin and interferon-mediated protection [PDF]
Tick-borne encephalitis virus (TBEV) is a member of the genus Flavivirus. It can cause serious infections in humans that may result in encephalitis/meningoencephalitis. Although several studies have described the involvement of specific genes in the host
Grubhoffer, Libor +6 more
core +2 more sources

