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Pathobiology of Japanese encephalitis virus infection.
Molecular Aspects of Medicine, 2021Japanese encephalitis virus (JEV) is a flavivirus, spread by the bite of carrier Culex mosquitoes. The subsequent disease caused is Japanese encephalitis (JE), which is the leading global cause of virus-induced encephalitis. The disease is predominant in the entire Asia-Pacific region with the potential of global spread.
Kiran Bala Sharma +2 more
semanticscholar +3 more sources
Vector Borne and Zoonotic Diseases, 2022
Japanese encephalitis virus (JEV) continues to cause significant numbers of human infections and fatalities despite the availability of efficacious vaccines.
C. Williams +3 more
semanticscholar +1 more source
Japanese encephalitis virus (JEV) continues to cause significant numbers of human infections and fatalities despite the availability of efficacious vaccines.
C. Williams +3 more
semanticscholar +1 more source
Japanese encephalitis virus glycoproteins
Virology, 1973Abstract Mature Japanese encephalitis (JE) virus, or N-form virus, contained three structural proteins: V-1, V-2, and V-3. The large membrane protein V-3 was glycosylated, whereas both V-1 (the small membrane protein) and V-2 (the nucleocapsid protein) were not. Intracellular (I-form), immature virions from infected chick embryo cells did not contain
D, Shapiro, K A, Kos, P K, Russel
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Japanese Encephalitis Virus-Infected Cells
2023RNA virus infections have been a leading cause of pandemics. Aided by global warming and increased connectivity, their threat is likely to increase over time. The flaviviruses are one such RNA virus family, and its prototypes such as the Japanese encephalitis virus (JEV), Dengue virus, Zika virus, West Nile virus, etc., pose a significant health burden
Kiran Bala, Sharma +2 more
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2020
Viruses belonging to the genus Flavivirus of the family Flaviviridae are the established human pathogens and their zoonotic potential has escalated in the last few decades. They are transmitted by vectors and accordingly grouped as tick-borne flaviviruses and mosquito-borne flaviviruses.
Samir Das +3 more
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Viruses belonging to the genus Flavivirus of the family Flaviviridae are the established human pathogens and their zoonotic potential has escalated in the last few decades. They are transmitted by vectors and accordingly grouped as tick-borne flaviviruses and mosquito-borne flaviviruses.
Samir Das +3 more
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Japanese encephalitis and Japanese encephalitis virus in mainland China
Reviews in Medical Virology, 2012SUMMARYJapanese encephalitis (JE), caused by Japanese encephalitis virus (JEV) infection, is the most important viral encephalitis in the world. Approximately 35,000–50,000 people suffer from JE every year, with a mortality rate of 10,000–15,000 people per year.
Yayun, Zheng +3 more
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Japanese encephalitis virus infection
2014Japanese encephalitis (JE) is a viral encephalitis caused by Japanese encephalitis virus (JEV), a single stranded positive sense RNA virus of the genus Flavivirus. The reservoir of JEV is wild birds and pigs; it is spread to humans by mosquitoes. There are approximately 68,000 cases and 15,000 deaths per year.
Michael J, Griffiths +2 more
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Transplacental Infection with Japanese Encephalitis Virus
Journal of Infectious Diseases, 1980During a widespread epidemic of Japanese encephalitis, five pregnant women affected by the illness were observed. The diagnosis of Japanese encephalitis virus (JEV) infection was established on the basis of clinical presentation, rising titers of hemagglutination-inhibiting antibody, and the presence of specific IgM antibodies.
U C, Chaturvedi +5 more
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The proteins of Japanese encephalitis virus
Virology, 1971Polyacrylamide gel electrophoresis of Japanese encephalitis virus (JEV) grown in both LLC-MK2 and chick embryo cell culture revealed three principal polypeptides with molecular weights of 8,700, 13,500, and 53,000 (V-1, V-2, and V-3, respectively). Infected chick cells that were treated with actinomycin D and cycloheximide contained seven polypeptides ...
D, Shapiro +3 more
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Neuropathogenesis of Japanese Encephalitis Virus
Journal of Neurovirology, 2002In the central nervous system, the Japanese encephalitis virus can replicate only in neurons. The mechanism of the type of neurotropism was analyzed. The susceptibility to Japanese encephalitis virus infection in the rat brain was closely associated with neuronal immaturity.
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