Results 181 to 190 of about 381,364 (391)

The impact of social relationships on the risk of stroke and post-stroke mortality: a systematic review and meta-analysis

BMC Public Health
Background The association between poor social relationships and post-stroke mortality remains uncertain, and the evidence regarding the relationship between poor social relationships and the risk of stroke is inconsistent.
Mingxian Meng, Zheng Ma, Hangning Zhou, Yanming Xie, Rui Lan, Shirui Zhu, Deyu Miao, Xiaoming Shen   +7 more
doaj   +1 more source

Encephalopathy of thiamine deficiency: studies of intracerebral mechanisms [PDF]

, 1968
David W. McCandless, Steven Schenker
openalex   +1 more source

Contemporary management of pain in cirrhosis: Toward precision therapy for pain

Hepatology, EarlyView., 2022
Abstract Chronic pain is highly prevalent in patients with cirrhosis and is associated with poor health‐related quality of life and poor functional status. However, there is limited guidance on appropriate pain management in this population, and pharmacologic treatment can be harmful, leading to adverse outcomes, such as gastrointestinal bleeding ...
Alexis Holman, Neehar Parikh, Dan J. Clauw, David A. Williams, Elliot B. Tapper   +4 more
wiley   +1 more source

Quercetin ameliorates liver fibrosis in Wilson disease and EMT involving suppression of the Hedgehog signaling pathway

Arabian Journal of Chemistry
Liver fibrosis is a fundamental pathological alteration observed in individuals with Wilson disease. Quercetin (Que) has shown potential in inhibiting fibrosis in various diseases.
Jie Chen, Wenming Yang, Ting Dong, Huaizhen Chen, Jing Zhang, Guocun Xu, Chenling Zhao, Jingyu Zeng, Lulu Tang   +8 more
doaj  

Da-Chuan-Xiong Decoction Ameliorates Sodium Sensitivity and Plasma Norepinephrine via Attenuation of Brain Oxidative Stress in the DOCA-Salt Hypertensive Rats

International Journal of Hypertension
Background. Da-Chuan-Xiong Decoction (DCXD) is an aqueous extract from a classic Chinese herbal formula composed of dried rhizomes of Ligusticum chuanxiong Hort and Gastrodia elata Bl. in the mass ratio of 4 : 1.
Qi Zhang, Hao Li, Shan Zhao, Fangfang Li, Yingying Tan   +4 more
doaj   +1 more source

BILIRUBIN ENCEPHALOPATHY IN THE GUNN RAT [PDF]

, 1967
Henry S. Schutta, Lois Johnson
openalex   +1 more source

Physiologically Based Pharmacokinetic Modeling to Predict Drug–Drug Interactions of Soticlestat as a Victim of CYP Induction and Inhibition, and as a Perpetrator of CYP and P–Glycoprotein Inhibition

Clinical Pharmacology in Drug Development, EarlyView.
Abstract Soticlestat (TAK‐935) is a cholesterol 24‐hydroxylase inhibitor. A physiologically‐based pharmacokinetic model has been developed to predict potential soticlestat drug–drug interactions (DDIs) using the Simcyp v20 Population‐based Simulator and verified with data from single‐/multiple‐rising‐dose and clinical DDI studies.
Hongxia Jia, T. Eric Ballard, Liming Zhang, Lawrence Cohen, Mackenzie C. Bergagnini‐Kolev, Ian E. Templeton, Hannah M. Jones, Wei Yin   +7 more
wiley   +1 more source

Circulating TREM2 as a noninvasive diagnostic biomarker for NASH in patients with elevated liver stiffness

Hepatology, EarlyView., 2022
Abstract Background and Aims Reliable noninvasive biomarkers are an unmet clinical need for the diagnosis of NASH. This study investigates the diagnostic accuracy of the circulating triggering receptor expressed on myeloid cells 2 (plasma TREM2) as a biomarker for NASH in patients with NAFLD and elevated liver stiffness.
Vineesh Indira Chandran, Charlotte Wilhelmina Wernberg, Mette Munk Lauridsen, Maria Kløjgaard Skytthe, Sofie Marchsteiner Bendixen, Frederik Tibert Larsen, Camilla Dalby Hansen, Lea Ladegaard Grønkjær, Majken Storm Siersbæk, Tina Di Caterino, Sönke Detlefsen, Holger Jon Møller, Lars Grøntved, Kim Ravnskjaer, Søren Kragh Moestrup, Maja Sofie Thiele, Aleksander Krag, Jonas Heilskov Graversen   +17 more
wiley   +1 more source

Tau PET and multimodal brain imaging in patients at risk for chronic traumatic encephalopathy. [PDF]

, 2019
ObjectiveTo characterize individual and group-level neuroimaging findings in patients at risk for Chronic Traumatic Encephalopathy (CTE).MethodsEleven male patients meeting criteria for Traumatic Encephalopathy Syndrome (TES, median age: 64) underwent ...
Baker, Suzanne L, Bourakova, Viktoriya, Chaudhary, Kiran, Edwards, Lauren, Gardner, Raquel C, Jagust, William J, Janabi, Mustafa, Kramer, Joel H, La Joie, Renaud, Lesman-Segev, Orit H, Miller, Bruce L, O'Neil, James P, Perry, David C, Rabinovici, Gil D, Sonni, Ida, Stephens, Melanie L, Tsai, Richard, Visani, Adrienne V   +17 more
core  

Experimental Cyanide Encephalopathy [PDF]

, 1967
Asao Hirano, Seymour Levine, H. M. Zimmerman   +2 more
openalex   +1 more source