Results 181 to 190 of about 216,601 (314)

Stiripentol: Unpublished results from the first phase 2 clinical trial in Lennox–Gastaut syndrome conducted in the early 1990s

Epilepsia, EarlyView.
Abstract Objective This study was undertaken to present the results of an exploratory phase 2 trial of stiripentol in Lennox–Gastaut syndrome (LGS). Methods This exploratory single‐blind, single‐arm, nonrandomized sequential‐period phase 2 study was conducted at four centers in France between January 1989 and August 1993.
Stéphane Auvin, Benjamin Serraz, Jérémie Lespinasse, Laurent Chancharme   +3 more
wiley   +1 more source

MECP2 Gene-Related Severe Neonatal Encephalopathy: A Rare Case in a Female Neonate. [PDF]

Cureus
Devi R, Gupta D, Rc PK, Singh P, Priyadarshi M, Chaurasia S, Basu S.   +6 more
europepmc   +1 more source

Clinical profile and risk factors of mortality in acute febrile encephalopathy in children: an experience from tertiary care center of central India

Rajkumar M. Meshram, Ashwini Patil, Sandeep Bhelkar, Priyanka Misal, Piyush Sachdev   +4 more
openalex   +1 more source

Genetic testing for familial epilepsies: Diagnostic yield and genetic findings

Epilepsia, EarlyView.
Abstract Objective Genetic testing has become a routine part of clinical epilepsy care. Family history is an indication for genetic testing, but the diagnostic yield, predictors of a genetic diagnosis, and association with familial patterns are not well understood.
Colin A. Ellis, Juliette Copeland, Isabella Velez, Karen L. Oliver, Hannah Shalaby, Aaron Baldwin, Caren Armstrong, Amanda Back, Brianna Berlin, Stacey Cohen, Vishnu Anand Cuddapah, Danielle deCampo, Holly Dubbs, Natalie Ginn, Alicia G. Harrison, Naomi Lewin, Laina Lusk, Eric D. Marsh, Shavonne L. Massey, Pamela Pojomovsky McDonnell, Jillian L. McKee, Xilma Ortiz‐Gonzalez, Anna J. Prentice, Katie Rose Sullivan, Sarah M. Ruggiero, Mark P. Fitzgerald, Ethan M. Goldberg, Ingo Helbig   +27 more
wiley   +1 more source

Metformin-Associated Encephalopathy as a Rare but Serious Adverse Effect: A Case Report. [PDF]

Cureus
Aoki A, Mizu D, Higashi H, Yamashita J.
europepmc   +1 more source

Rhubarb-based Chinese herbal formulae for hepatic encephalopathy: a systematic review and Meta-analysis

, 2017
Ning Zhang, Zhou Shuangnan, Xiao Xiao-he, Wang Zhen, Yunfeng Bai, Tingting He, Chao Zhou, Yao Wang, Kun Zhou, Wang Zhong-Xia, Liu Bing, Larry J. Prokop, Matthew C. Hernandez, Li Jun, Man Gong   +14 more
openalex   +1 more source

Soticlestat as an adjunctive therapy in children and young adults with Dravet syndrome

Epilepsia, EarlyView.
Overview of the phase 3 trial evaluating soticlestat as adjunctive therapy in children and young adults with Dravet syndrome. Abstract Objective This study evaluated the efficacy, safety, and tolerability of soticlestat as adjunctive therapy in children and young adults with Dravet syndrome (DS).
Joseph Sullivan, Kette Valente, Vicente Villanueva, Adam Strzelczyk, Rima Nabbout, Eiji Nakagawa, Yuehua Zhang, Marta Zolnowska, Yasir Khan, Cheng Dong, Samuel Hsiao, Sarah I. Sheikh, Philipp von Rosenstiel, Mahnaz Asgharnejad, Venkatesha Murthy   +14 more
wiley   +1 more source

Acute Hemorrhagic Necrotizing Encephalopathy in a COVID-19 Patient With a Response to Intravenous Immunoglobulin Therapy. [PDF]

Am J Case Rep
Almeer FS, Alkoheji HK, Zayed ME, Al-Hilly AJ, Abduljabar Hussein O.   +4 more
europepmc   +1 more source

The Case for Involvement of Spiroplasma in the Pathogenesis of Transmissible Spongiform Encephalopathies [PDF]

, 2014
Frank O. Bastian
openalex   +1 more source

Lactate receptor HCAR1 in neonatal hypoxic–ischemic seizures

Epilepsia, EarlyView.
Abstract Hydroxycarboxylic acid receptor 1 (HCAR1) is a G‐protein‐coupled lactate receptor expressed in the brain and plays a role in neuronal excitability and repair after injury. Hypoxic–ischemic encephalopathy (HIE) is the most common cause of brain injury and seizures in term neonates.
Jennifer Burnsed, Angelina June, Maria Marlicz, Emmy Zucker, Ellie Kain‐Kuzniewski, Hannah Mulhern, Leanne Maharaj, John Williamson, Chengsan Sun, Suchitra Joshi, Huayu Sun, Jaideep Kapur   +11 more
wiley   +1 more source