Results 131 to 140 of about 145,080 (300)

The aspect of vector control using the asynchronous traction motor in locomotives

Transport, 2009
The article examines curves controlling asynchronous traction motors increasingly used in locomotive electric drives the main task of which is to create a tractive effort‐speed curve of an ideal locomotive Fk = f(v), including a hyperbolic area the curve
Lionginas Liudvinavičius, Leonas Povilas Lingaitis, Stasys Dailydka, Virgilijus Jastremskas   +3 more
doaj  

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

Molecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Dimension Reduction using Dual-Featured Auto-encoder for the Histological Classification of Human Lungs Tissues [PDF]

Histopathology images are visual representations of tissue samples that have been processed and examined under a microscope in order to establish diagnoses for various disorders.
Khan, M.A., Ouahada, K., Shahzad, T., Aamir, M., Nawi, M. N., Ashraf, A.   +5 more
core   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Visually Lossless Encoder and Lossless Encoder Configurations under Low Delay Condition.

, 2016
Visually Lossless Encoder and Lossless Encoder Configurations under Low Delay Condition.
Yuan Gao (159945), Guandong Gao (2575564), Yueying Wu (747404), Kebin Jia (2575561), Pengyu Liu (2575567)   +4 more
core   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

X-FuseRLSTM: A Cross-Domain Explainable Intrusion Detection Framework in IoT Using the Attention-Guided Dual-Path Feature Fusion and Residual LSTM

Sensors
Due to domain variability and developing attack tactics, intrusion detection in heterogeneous and dynamic IoT systems is still a crucial challenge. For cross-domain intrusion detection, this paper proposes a novel algorithm, X-FuseRLSTM, a dual-path ...
Adel Alabbadi, Fuad Bajaber
doaj   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

EMC Design of Metro Train Traction and Brake Force Instruction Signal

机车电传动, 2012
To improve the immunity of the traction and brake force instruction signal and confirm signal transmission reliability, transformation, transmitting and screening design method of the traction and brake fore instruction signal was deeply analyzed, and ...
GUO Zhen-tong, LI Bao-xia
doaj  

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

Molecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler, Bilal A. Lone, Ecem Unal, A. Rouf Banday   +3 more
wiley   +1 more source