Results 191 to 200 of about 181,238 (294)

Single‐Cell Dissection Reveals Immune Dysregulation After CD5 or CD7‐Directed Chimeric Antigen Receptor T‐Cell Therapy

Advanced Science, EarlyView.
Single‐cell RNA/TCR/BCR sequencing reveals that 5CAR therapy in T‐ALL induces T‐cell exhaustion, reduces EBV‐associated TCRs, lowers TCR/BCR diversity, and increases NK/DC/monocyte activation and function. In contrast, 7CAR therapy reduces multiple pathogen‐associated TCRs, enhances NK cell activation and function, decreases monocyte activation, and ...
Yuechen Luo, Haixiao Zhang, Kaiting Tang, Yiming Wang, Huajiang Dong, Wei Qi, Lingling Shan, Yue Tan, Liping Zhao, Jun Shi, Erlie Jiang, Jing Pan, Xiaoming Feng   +12 more
wiley   +1 more source

Dynamic brain mechanisms supporting salient memories under cortisol. [PDF]

Sci Adv
Huang Y, O'Connor D, Harris BB, Sinha R, Constable RT, Goldfarb EV.   +5 more
europepmc   +1 more source

Discovery of a Novel and Potent Kir4.1 Inhibitor as a Safe and Rapid‐Onset Antidepressant Agent in Mice

Advanced Science, EarlyView.
The preferred derivative JX3212 demonstrates strong inhibitory activity against Kir4.1 with favorable druggability and shows significant antidepressant efficacy in vivo. Abstract Major depressive disorder is a serious psychiatric disorder for which novel and fast‐acting antidepressants are required.
Sisi Wang, Xiaoyu Zhou, Mengdan Li, Chao Zhang, Haiyan Xu, Jingyi He, Li Zhan, Yueling Gu, Hao Gu, Tianyu Tu, Hanfang Liu, Taotao Lu, Yueming Zheng, Jian Li, Zhaobing Gao, Yixiang Xu   +15 more
wiley   +1 more source

Memory and the Korsakoff syndrome: Not an encoding deficit but a problem of conscious recollection at retrieval? [PDF]

, 2005
Géry d’Ydewalle, Ilse Van Damme
openalex  

Robust spatial memory maps encoded in networks with transient connections [PDF]

, 2017
Andrey Babichev, Dmitriy Morozov, Yuri Dabaghian   +2 more
openalex   +1 more source

Single‐Field Evolution Rule Governs the Dynamics of Representational Drift in Mouse Hippocampal Dorsal CA1 Region

Advanced Science, EarlyView.
Long‐term hippocampal place‐code dynamics are investigated using calcium imaging across weeks of maze navigation. Analyses reveal a novelty‐irrelevant Single‐Field Evolution Rule (SFER), where active fields promote persistence and inactive fields decline.
Cong Chen, Shuyang Yao, Sihui Cheng, Jiayi Tian, Ang Li, Yusen Yan, Xiang Zhang, Yuanjing Liu, Yumeng Wang, Qichen Cao, Chenglin Miao   +10 more
wiley   +1 more source

Long-term effects of bifrontal transcranial alternating current stimulation on verbal working memory and episodic memory in young healthy adults. [PDF]

Sci Rep
Raviv H, Mashal N, Meiron O.
europepmc   +1 more source

The Geometry of Layer 2/3 Cortical Sound Processing in Slow Wave Sleep

Advanced Science, EarlyView.
Sleep is associated with a sensory disconnection whose mechanisms remain elusive. Large neuronal population recordings in the auditory cortex revealed that, in NREM sleep, the neural code for sounds is highly similar to wakefulness, but coordinated modulations of neuron responsiveness intermittently disconnect the local cortical networks from sensory ...
Allan Muller, Anton Filipchuk, Sophie Bagur, Brice Bathellier   +3 more
wiley   +1 more source

Interactions between memory and new learning: Insights from fMRI multivoxel pattern analysis

Frontiers in Systems Neuroscience, 2016
Marlieke T R Van Kesteren, Marlieke T R Van Kesteren, Thackery I Brown, Anthony D Wagner   +3 more
doaj   +1 more source

The Otter and the Cleaver: Exploring the Neural Underpinnings of Unitization Using the Gestalt Principle of Proximity. [PDF]

J Cogn Neurosci
Dennis NA, Overman AA, Carpenter CM, Becker A, West JT, Chase SO.   +5 more
europepmc   +1 more source