Results 221 to 230 of about 1,239,580 (286)

Transcriptomic analysis and machine learning have identified shared diagnostic genes and a possible mechanism linking bipolar disorder and epilepsy. [PDF]

Medicine (Baltimore)
Zhang Y, Xu Y, Huo C.
europepmc   +1 more source

Drug‐Induced Cuproptosis Defines the Therapeutic Window of Celecoxib in Intervertebral Disc Degeneration via the HSP90‐RBX1 Axis

Advanced Science, EarlyView.
This study reveals the dual role of celecoxib in intervertebral disc degeneration. While low concentrations are protective, high concentrations induce toxicity by upregulating HSP90, which synergizes with USP15 to deubiquitinate and stabilize RBX1. This leads to degradation of COMMD1/ATP7B, copper dyshomeostasis, and ultimately, cuproptosis.
Youfeng Guo, Hongju Xiao, Shenghao Ba, Yu Zhou, Bijun Wang, Bin Yu, Yufeng Huang, Haihong Zhao, Zhefan Stephen Chen, Na Shen, Zhaoyu Ba, Desheng Wu   +11 more
wiley   +1 more source

Integrative transcriptomic and machine learning analysis identifies PYCARD and IFI30 as immune-lysosomal biomarkers of ANCA-associated glomerulonephritis. [PDF]

Ren Fail
Bei L, Liao J, Yang Z, Li S, Huang M, Lei L.   +5 more
europepmc   +1 more source

Bioinformatics analysis and population sample validation of ferroptosis-related genes in coronary heart disease: A case-control study. [PDF]

Medicine (Baltimore)
Li LH, Chen CH, Dong QH, Xie YB.
europepmc   +1 more source

Identification of exosome miRNAs regulated by SPHK2 in human glioma cells. [PDF]

Front Oncol
Liu J, Zhao H, Liu X, Guan X, Guo Q, Xu Y, Qiu J.   +6 more
europepmc   +1 more source

Enhanced Monacolin K Production in Monascus purpureus Via Mutagenesis and Nitrogen Source Optimization. [PDF]

J Basic Microbiol
Yang C, Yajing Y, Housheng H.
europepmc   +1 more source

Sijunzi decoction ameliorates geriatric sarcopenia by improving muscle strength, quality, and functions. [PDF]

Medicine (Baltimore)
Yue Y, Xu M, Xu Z, Qian L, Dou L, Huang J.   +5 more
europepmc   +1 more source

European Encyclopedia Conference 2024, Oslo, Norway, 15−16 May

Studia Lexicographica
Erik Bolstad, Nataša Jermen
doaj  

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2013
exaly   +4 more sources