Results 261 to 270 of about 1,225,935 (368)
Structural Variations Associated with Adaptation and Coat Color in Qinghai‐Tibetan Plateau Cattle
This study reveals the landscape of structural variants in Qinghai‐Tibetan Plateau cattle through long‐read sequencing. Discoveries include metabolic and oxygen‐regulation gene variants, along with a 2‐Mb KIT‐containing inversion and translocations responsible for cattle gray coat. These findings highlight the significant role of structural variants in
Xiaoting Xia+39 more
wiley +1 more source
Molecular insights into gender-specific differences in rheumatoid arthritis: A study using high-throughput sequencing and Mendelian randomization. [PDF]
Wang D+9 more
europepmc +1 more source
pMM‐PCL, made up of pretreated macrophage menbrane and polycaprolactone, boasts the adsorption of harmful myelin debris in the microenvironment of spinal cord injury. Abstract After spinal cord injury (SCI), a mass of myelin debris derived from injured myelin sheath will be consistently generated and induce macrophages to be foam cells.
Yuchen Zhou+7 more
wiley +1 more source
Early diagnosis of acute myocardial infarction via hub genes identified by integrated weighted gene co-expression network analysis. [PDF]
Huang K+8 more
europepmc +1 more source
Prevention and treatment of diabetic kidney disease (DKD) have become a major global public health challenge. This study shed new light on the underlying pathogenic mechanisms of podocyte injury in DKD and highlights the therapeutic potential of mitigating podocyte injury through inhibition of the RIPK3/NF‐κB p65‐mediated inflammatory response as a ...
Lu'an Li+10 more
wiley +1 more source
Correction: Chen et al. Metabolomics-Based Study on the Anticonvulsant Mechanism of <i>Acorus tatarinowii</i>: GABA Transaminase Inhibition Alleviates PTZ-Induced Epilepsy in Rats. <i>Metabolites</i> 2025, <i>15</i>, 175. [PDF]
Chen L, Li J, Fang C, Wang J.
europepmc +1 more source
This study identifies a novel mechanism of nasopharyngeal carcinoma (NPC) cisplatin chemoresistance that DDAH1 expression is associated with cisplatin resistance in NPC cells primarily through the enhancement of the phosphoinositide Janus kinase 2 (JAK2)‐signal transducer and activator of transcription 3 (STAT3) pathway.
Jin‐Hao Yang+10 more
wiley +1 more source
Cellular Landscape of Synovial Chondromatosis Synovium Revealed by Single-Cell RNA Sequencing. [PDF]
Zhao H+10 more
europepmc +1 more source
Biosynthesis rates of 13 FFAs are quantitatively calculated in 15 tissues from glucose and an analytical framework to quantitatively calculate inter‐tissue communications of fatty acids between the liver and other tissues is developed. Moreover, the approach is extended to aging condition and a system‐wide decline of fatty acid synthesis in peripheral ...
Beizi Xing+4 more
wiley +1 more source